| ZFIN ID: ZDB-EXP-210720-6 |
Experiment Conditions Description: chemical treatment by environment: nicotine, chemical treatment by environment: amisulpride
| chemical treatment by environment: nicotine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | nicotine |
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| Synonyms: | (+-)-3-(1-Methyl-2-pyrrolidinyl)pyridine, (+-)-nicotine, (R,S)-nicotine, (RS)-nicotine, 3-(1-methylpyrrolidin-2-yl)pyridine, nicotin, nikotin, rac-3-(1-methylpyrrolidin-2-yl)pyridine |
| Definition: | A racemate composed of equimolar amounts of (R)- and (S)-nicotine. |
| Ontology: | ChEBI [CHEBI:18723] ( EBI ) |
| chemical treatment by environment: amisulpride |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | amisulpride |
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| Synonyms: | 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide, 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-o-anisamide, 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide, Aminosultopride, amisulprida, amisulpride, amisulpridum |
| Definition: | A member of the class of benzamides resulting from the formal condensation of the carboxy group of 4-amino-5-(ethylsulfonyl)-2-methoxybenzoic acid with the primary amino group of 2-(aminomethyl)-1-ethylpyrrolidine. It is a potent, selective dopamine D2 and D3 receptor antagonist. It is an atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects. |
| Ontology: | ChEBI [CHEBI:64045] ( EBI ) |
| Publication: | García-González et al., 2020 |
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