| ZFIN ID: ZDB-EXP-210401-9 |
Experiment Conditions Description: light ablation: brain vasculature, chemical treatment by environment: NSC 23766
| light ablation: brain vasculature |
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| Name: | light ablation |
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| Synonyms: | |
| Definition: | Experimental condition which uses focused light to ablate an anatomical structure or cell. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000170] |
| Name: | brain vasculature |
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| Synonyms: | |
| Definition: | Is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the brain. |
| Ontology: | Anatomy Ontology [ZFA:0000099] |
| chemical treatment by environment: NSC 23766 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | NSC 23766 |
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| Synonyms: | N(6)-(2-{[5-(diethylamino)pentan-2-yl]amino}-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine, N6-[2-[5-(diethylamino)pentan-2-ylamino]-6-methyl-4-pyrimidinyl]-2-methylquinoline-4,6-diamine, NSC-23766, NSC23766 |
| Definition: | An aminopyrimidine that is 6-methylpyrimidine-2,4-diamine in which the amino groups at positions 2 and 4 are substituted by 5-(diethylamino)pentan-2-yl and 4-amino-2-methylquinolin-6-yl groups respectively. An inhibitor of the signalling G-protein known as RAC1 (Ras-related C3 botulinum toxin substrate 1). |
| Ontology: | ChEBI [CHEBI:144984] ( EBI ) |
| Publication: | Liu et al., 2016 |
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