| ZFIN ID: ZDB-EXP-210401-5 |
Experiment Conditions Description: light ablation: brain vasculature, chemical treatment by environment: blebbistatin
| light ablation: brain vasculature |
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| Name: | light ablation |
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| Synonyms: | |
| Definition: | Experimental condition which uses focused light to ablate an anatomical structure or cell. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000170] |
| Name: | brain vasculature |
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| Synonyms: | |
| Definition: | Is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the brain. |
| Ontology: | Anatomy Ontology [ZFA:0000099] |
| chemical treatment by environment: blebbistatin |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | blebbistatin |
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| Synonyms: | (+/-)-blebbistatin, 3a-hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one |
| Definition: | A pyrroloquinoline that is 1,2,3,3a-tetrahydro-H-pyrrolo[2,3-b]quinolin-4-one substituted by a hydroxy group at position 3a, a methyl group at position 6 and a phenyl group at position 1. It acts as an inhibitor of ATPase activity of non-muscle myosin II. |
| Ontology: | ChEBI [CHEBI:75379] ( EBI ) |
| Publication: | Liu et al., 2016 |
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