| ZFIN ID: ZDB-EXP-210203-8 |
Experiment Conditions Description: chemical treatment by environment: ANA-12
| chemical treatment by environment: ANA-12 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | ANA-12 |
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| Synonyms: | ANA12, N-{2-[(2-oxoazepan-3-yl)carbamoyl]phenyl}-1-benzothiophene-2-carboxamide, TrkB antagonist |
| Definition: | A secondary carboxamide that is anthranilic acid in which the carboxy group has undergone condensation with the primary amino group of alpha-amino-epsilon-caprolactam, while the aryl-amino group has undergone condensation with the carboxy group of 1-benzothiophene-2-carboxylic acid. It is a selective, non-competitive antagonist of tropomyosin receptor kinase B (TrkB, also known as tyrosine receptor kinase B). |
| Ontology: | ChEBI [CHEBI:140465] ( EBI ) |
| Publication: | Kedra et al., 2020 |
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