ZFIN ID: ZDB-EXP-201103-21
Experiment Conditions Description: chemical treatment by environment: EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor, chemical treatment by environment: doxycycline
chemical treatment by environment: EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
Synonyms: ABL inhibitor, ABL inhibitors, ABL1 inhibitor, ABL1 inhibitors, ABL2 inhibitor, ABL2 inhibitors, ABLL inhibitor, ABLL inhibitors, ACK1 inhibitor, ACK1 inhibitors, ACK2 inhibitor, ACK2 inhibitors, AGMX1 inhibitor, AGMX1 inhibitors, ARG inhibitor, ARG inhibitors, ATK inhibitor, ATK inhibitors, ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) inhibitor, ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) inhibitors, BLK inhibitor, BLK inhibitors, Bmk inhibitor, Bmk inhibitors, BMX inhibitor, BMX inhibitors, BRK inhibitor, BRK inhibitors, Bruton's tyrosine kinase inhibitor, Bruton's tyrosine kinase inhibitors, Bsk inhibitor, Bsk inhibitors, BTK inhibitor, BTK inhibitors, BTKL inhibitor, BTKL inhibitors, CAKb inhibitor, CAKb inhibitors, Cdgip inhibitor, Cdgip inhibitors, CHK inhibitor, CHK inhibitors, CSK inhibitor, CSK inhibitors, CTK inhibitor, CTK inhibitors, CYL inhibitor, CYL inhibitors, cytoplasmic protein tyrosine kinase inhibitor, cytoplasmic protein tyrosine kinase inhibitors, EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitors, EC 2.7.10.2 inhibitor, EC 2.7.10.2 inhibitors, EMT inhibitor, EMT inhibitors, ETK inhibitor, ETK inhibitors, Fadk inhibitor, Fadk inhibitors, FAK inhibitor, FAK inhibitors, FAK2 inhibitor, FAK2 inhibitors, FER inhibitor, FER inhibitors, Fert1/2 inhibitor, Fert1/2 inhibitors, FES inhibitor, FES inhibitors, FGR inhibitor, FGR inhibitors, focal adhesion kinase inhibitor, focal adhesion kinase inhibitors, FPS inhibitor, FPS inhibitors, FRK inhibitor, FRK inhibitors, FYN inhibitor, FYN inhibitors, HCK inhibitor, HCK inhibitors, HCTK inhibitor, HCTK inhibitors, HYL inhibitor, HYL inhibitors, IMD1 inhibitor, IMD1 inhibitors, ITK inhibitor, ITK inhibitors, IYK inhibitor, IYK inhibitors, JAK1 inhibitor, JAK1 inhibitors, JAK2 inhibitor, JAK2 inhibitors, JAK3 inhibitor, JAK3 inhibitors, Janus kinase 1 inhibitor, Janus kinase 1 inhibitors, Janus kinase 2 inhibitor, Janus kinase 2 inhibitors, Janus kinase 3 inhibitor, Janus kinase 3 inhibitors, Janus kinase inhibitor, JTK1 inhibitor, JTK1 inhibitors, JTK9 inhibitor, JTK9 inhibitors, L-JAK inhibitor, L-JAK inhibitors, LCK inhibitor, LCK inhibitors, LSK inhibitor, LSK inhibitors, LYN inhibitor, LYN inhibitors, MATK inhibitor, MATK inhibitors, non-specific protein-tyrosine kinase (EC 2.7.10.2) inhibitor, non-specific protein-tyrosine kinase (EC 2.7.10.2) inhibitors, Ntk inhibitor, Ntk inhibitors, p60c-src protein tyrosine kinase inhibitor, p60c-src protein tyrosine kinase inhibitors, PKB inhibitor, PKB inhibitors, PSCTK inhibitor, PSCTK inhibitors, PSCTK1 inhibitor, PSCTK1 inhibitors, PSCTK2 inhibitor, PSCTK2 inhibitors, PSCTK4 inhibitor, PSCTK4 inhibitors, PSCTK5 inhibitor, PSCTK5 inhibitors, PTK2 inhibitor, PTK2 inhibitors, PTK2B inhibitor, PTK2B inhibitors, PTK6 inhibitor, PTK6 inhibitors, PYK2 inhibitor, PYK2 inhibitors, RAFTK inhibitor, RAFTK inhibitors, RAK inhibitor, RAK inhibitors, Rlk inhibitor, Rlk inhibitors, Sik inhibitor, Sik inhibitors, SLK inhibitor, SLK inhibitors, SRC inhibitor, SRC inhibitors, SRC2 inhibitor, SRC2 inhibitors, SRK inhibitor, SRK inhibitors, SRM inhibitor, SRM inhibitors, SRMS inhibitor, SRMS inhibitors, STD inhibitor, STD inhibitors, SYK inhibitor, SYK inhibitors, SYN inhibitor, SYN inhibitors, Tck inhibitor, Tck inhibitors, TEC inhibitor, TEC inhibitors, TNK1 inhibitor, TNK1 inhibitors, Tsk inhibitor, Tsk inhibitors, TXK inhibitor, TXK inhibitors, TYK2 inhibitor, TYK2 inhibitors, TYK3 inhibitor, TYK3 inhibitors, YES1 inhibitor, YES1 inhibitors, YK2 inhibitor, YK2 inhibitors, ZAP70 inhibitor, ZAP70 inhibitors
Definition: An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that specifically blocks the action of non-specific protein-tyrosine kinase (EC 2.7.10.2).
Ontology: ChEBI [CHEBI:76617]  ( EBI )
chemical treatment by environment: doxycycline
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: doxycycline
Synonyms: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, 5-hydroxy-alpha-6-deoxytetracycline, 6alpha-deoxy-5-oxytetracycline, doxiciclina, Doxycyclin, doxycycline, doxycycline (anhydrous), doxycyclinum, Jenacyclin, Supracyclin, Vibramycin
Definition: Tetracycline in which the 5beta-hydrogen is replaced by a hydroxy group, while the 6alpha-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis.
Ontology: ChEBI [CHEBI:50845]  ( EBI )
Publication: Yang et al., 2019