| ZFIN ID: ZDB-EXP-200116-11 |
Experiment Conditions Description: surgical manipulation: telencephalon, chemical treatment: dexamethasone
| surgical manipulation: telencephalon |
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| Name: | surgical manipulation |
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| Synonyms: | |
| Definition: | Experimental condition that involves manual or instrumental techniques to alter anatomical structures. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000176] |
| Name: | telencephalon |
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| Synonyms: | |
| Definition: | The anterior and dorsal forebrain neuromere. In ray-finned fishes and most pronounced in teleosts the roof plate of the embryonic telencephalon extends laterally with the effect that the paired alar plates forming the hemispheric walls roll out lateroventrally in a process called eversion. This is unlike the development in other vertebrate groups. From Neuroanatomy of the Zebrafish Brain. |
| Ontology: | Anatomy Ontology [ZFA:0000079] |
| chemical treatment: dexamethasone |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | dexamethasone |
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| Synonyms: | (11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 1-dehydro-16alpha-methyl-9alpha-fluorohydrocortisone, 16alpha-methyl-9alpha-fluoro-1-dehydrocortisol, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, 9alpha-fluoro-16alpha-methylprednisolone, Aeroseb-Dex, Auxiron, Azium, Calonat, Corson, Cortisumman, Decacort, Decadron, Decaject, Decalix, Decameth, Dexacortal, Dexacortin, dexametasona, dexamethasone, dexamethasonum, Dexason, Dexasone, DexPak, Diodex, fluormethylprednisolone, Hexadrol, Maxidex, Millicorten, Oradexon, Ozurdex, Solurex, Zema-Pak |
| Definition: | A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids. |
| Ontology: | ChEBI [CHEBI:41879] ( EBI ) |
| Publication: | Rastegar et al., 2019 |
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