| ZFIN ID: ZDB-EXP-190808-4 |
Experiment Conditions Description: transection: spinal cord, chemical treatment by environment: pomalidomide
| transection: spinal cord |
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| Name: | transection |
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| Synonyms: | |
| Definition: | Cutting transversly of an organ or tissue. Type of cutting often used to divide the spinal cord to investigate neural regeneration in zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000181] |
| Name: | spinal cord |
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| Synonyms: | medulla spinalis, spinal cord structure |
| Definition: | |
| Ontology: | Anatomy Ontology [ZFA:0000075] |
| chemical treatment by environment: pomalidomide |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | pomalidomide |
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| Synonyms: | 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide, 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione, 4-amino-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione, 4-Aminothalidomide, CC 4047, CC-4047, pomalidomide, Pomalyst |
| Definition: | An aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies. |
| Ontology: | ChEBI [CHEBI:72690] ( EBI ) |
| Publication: | Tsarouchas et al., 2018 |
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