ZFIN ID: ZDB-EXP-190708-21 |
Experiment Conditions Description: chemical treatment by environment: fulvestrant, chemical treatment by environment: genistein
chemical treatment by environment: fulvestrant |
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Name: | chemical treatment by environment |
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Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | fulvestrant |
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Synonyms: | (7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diol, 7alpha-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17beta-diol, Faslodex, fulvestrant, fulvestrantum, ICI 182780, ICI-182780 |
Definition: | A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer. |
Ontology: | ChEBI [CHEBI:31638] ( EBI ) |
chemical treatment by environment: genistein |
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Name: | chemical treatment by environment |
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Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | genistein |
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Synonyms: | 4',5,7-trihydroxyisoflavone, 5,7,4'-Trihydroxyisoflavone, 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, GENISTEIN, Prunetol, Sophoricol |
Definition: | A 7-hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties. |
Ontology: | ChEBI [CHEBI:28088] ( EBI ) |
Publication: | Carroll et al., 2014 |
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