| ZFIN ID: ZDB-EXP-190625-13 |
Experiment Conditions Description: transection: caudal fin, chemical treatment by injection: EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor, chemical treatment by environment: prostaglandin E2
| transection: caudal fin |
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| Name: | transection |
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| Synonyms: | |
| Definition: | Cutting transversly of an organ or tissue. Type of cutting often used to divide the spinal cord to investigate neural regeneration in zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000181] |
| Name: | caudal fin |
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| Synonyms: | tail, tail fin |
| Definition: | Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines. |
| Ontology: | Anatomy Ontology [ZFA:0001058] |
| chemical treatment by injection: EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor |
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| Synonyms: | 15-lipoxygenase inhibitor, 15-lipoxygenase inhibitors, 15-LOX inhibitor, 15-LOX inhibitors, arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitor, arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitors, arachidonate 15-lipoxygenase inhibitor, arachidonate 15-lipoxygenase inhibitors, arachidonate:oxygen 15-oxidoreductase inhibitor, arachidonate:oxygen 15-oxidoreductase inhibitors, EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitors, EC 1.13.11.33 inhibitor, EC 1.13.11.33 inhibitors, linoleic acid omega(6)-lipoxygenase inhibitor, linoleic acid omega(6)-lipoxygenase inhibitors, omega(6) lipoxygenase inhibitor, omega(6) lipoxygenase inhibitors |
| Definition: | A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33). |
| Ontology: | ChEBI [CHEBI:64996] ( EBI ) |
| chemical treatment by environment: prostaglandin E2 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | prostaglandin E2 |
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| Synonyms: | (15S)-prostaglandin E2, (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate, (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate, (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid, (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid, Cervidil, Cerviprime, Cerviprost, Dinoproston, dinoprostona, dinoprostone, dinoprostonum, Enzaprost E, Glandin-E2, Minprositin E2, Minprostin E2, PGE2, Prepidil, Propess, Prostaglandin E2, Prostarmon E, Prostenone, Prostin, Prostin E2, U 12062, U-12,062, U-12062 |
| Definition: | Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins. |
| Ontology: | ChEBI [CHEBI:15551] ( EBI ) |
| Publication: | Loynes et al., 2018 |
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