| ZFIN ID: ZDB-EXP-161220-8 |
Experiment Conditions Description: chemical treatment by environment: afimoxifene, chemical treatment by environment: DAPT
| chemical treatment by environment: afimoxifene |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | afimoxifene |
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| Synonyms: | 4-hydroxytamoxifen, 4-monohydroxytamoxifen, 4-OHT, afimoxifene |
| Definition: | A tertiary amino compound that is tamoxifen in which the phenyl group which is in a Z- relationship to the ethyl substituent is hydroxylated at the para- position. It is the active metabolite of tamoxifen. |
| Ontology: | ChEBI [CHEBI:44616] ( EBI ) |
| chemical treatment by environment: DAPT |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | DAPT |
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| Synonyms: | gamma-secretase inhibitor IX, GSI-IX, tert-butyl (2S)-({N-[(3,5-difluorophenyl)acetyl]-L-alanyl}amino)(phenyl)acetate, tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate |
| Definition: | A dipeptide consisting of alanylphenylglycine derivatised as a 3,5-difluorophenylacetamide at the amino terminal and a tert-butyl ester at the carboxy terminal. It is a gamma-secretase inhibitor. |
| Ontology: | ChEBI [CHEBI:86193] ( EBI ) |
| Publication: | Huang et al., 2016 |
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