| ZFIN ID: ZDB-EXP-160720-2 |
Experiment Conditions Description: chemical treatment: roxadustat
| chemical treatment: roxadustat |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | roxadustat |
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| Synonyms: | ASP1517, FG 4592, FG-4592, FG4592, HIF prolyl-hydroxylase inhibitor, N-[(4-hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]glycine, roxadustat, roxadustatum |
| Definition: | An N-acylglycine resulting from the formal condensation of the amino group of glycine with the carboxy group of 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid. It is an inhibitor of hypoxia inducible factor prolyl hydroxylase (HIF-PH). |
| Ontology: | ChEBI [CHEBI:132774] ( EBI ) |
| Publication: | Jain et al., 2016 |
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