| ZFIN ID: ZDB-EXP-160525-15 |
Experiment Conditions Description: chemical treatment: rolipram, chemical treatment: PD 0325901
| chemical treatment: rolipram |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | rolipram |
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| Synonyms: | 4-(3-(Cyclopentyloxy)-4-methoxyphenyl)-2-pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one, rolipram, rolipramum, ZK 62711 |
| Definition: | A member of the lclass of pyrrolidin-2-ones that is pyrrolidin-2-one bearing a 3-(cyclopentyloxy)-4-methoxyphenyl substituent at the 4-position. It is a type IV-specific phosphodiesterase (PDE4) inhibitor. |
| Ontology: | ChEBI [CHEBI:104872] ( EBI ) |
| chemical treatment: PD 0325901 |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | PD 0325901 |
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| Synonyms: | N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide, PD 325901, PD-0325901, PD-325901, PD0325901 |
| Definition: | A hydroxamic acid ester that is benzhydroxamic acid (N-hydroxybenzamide) in which the hydroxamic acid group has been converted to the corresponding 2,3-dihydroxypropyl ester and in which the benzene ring has been substituted at position 2 by a (2-fluoro-4-iodophenyl)amino group and at positions 3 and 4 by fluorines (the R enantiomer). |
| Ontology: | ChEBI [CHEBI:88249] ( EBI ) |
| Publication: | Lundegaard et al., 2015 |
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