| ZFIN ID: ZDB-EXP-150508-14 |
Experiment Conditions Description: amputation: caudal fin, chemical treatment: PP2
| amputation: caudal fin |
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| Name: | amputation |
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| Synonyms: | |
| Definition: | Resection condtion in which all or part of an extremity such as the fin or tail are removed. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000172] |
| Name: | caudal fin |
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| Synonyms: | tail, tail fin |
| Definition: | Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines. |
| Ontology: | Anatomy Ontology [ZFA:0001058] |
| chemical treatment: PP2 |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | PP2 |
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| Synonyms: | 1-tert-butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, AG 1879, AG-1879, AG1879 |
| Definition: | A member of the class of pyrazolopyrimidine that is pyrazolo[3,4-d]pyrimidin-4-amine bearing additional tert-butyl and 4-chlorophenyl substituents at positions 1 and 3 respectively. It is a potent ATP-competitive inhibitor of the Src family of protein tyrosine kinases. |
| Ontology: | ChEBI [CHEBI:78331] ( EBI ) |
| Publication: | Tauzin et al., 2014 |
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