ZFIN ID: ZDB-EXP-140729-6 |
Experiment Conditions Description: chemical treatment: lonafarnib
chemical treatment: lonafarnib |
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Name: | chemical treatment |
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Synonyms: | |
Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
Name: | lonafarnib |
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Synonyms: | 4-(2-{4-[(11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidin-1-yl}-2-oxoethyl)piperidine-1-carboxamide, lonafarnib, lonafarnibum, SCH 66336 |
Definition: | A 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide that has R configuration. It is used as oral farnesyltransferase inhibitor. |
Ontology: | ChEBI [CHEBI:47097] ( EBI ) |
Publication: | Mathews et al., 2014 |
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