| ZFIN ID: ZDB-EXP-131205-3 |
Experiment Conditions Description: chemical treatment: 2-amino-5-phosphonopentanoic acid, chemical treatment: bicuculline, chemical treatment: tubocurarine, chemical treatment: 6-Cyano-7-nitroquinoxaline-2,3-dione, chemical treatment: tetrodotoxin
| chemical treatment: 2-amino-5-phosphonopentanoic acid |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | 2-amino-5-phosphonopentanoic acid |
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| Synonyms: | 2-Amino-5-phosphonovaleric acid, 2-Amino-5-phosphopentanoic acid, 2-Amino-5-phosphovaleric acid, 5-phosphononorvaline |
| Definition: | The 5-phosphono derivative of 2-aminopentanoic acid; acts as an N-methyl-D-aspartate receptor antagonist. |
| Ontology: | ChEBI [CHEBI:138644] ( EBI ) |
| chemical treatment: bicuculline |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | bicuculline |
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| Synonyms: | (6R)-6-[(5S)-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one, Bicculine, Bicucullin, Bicuculline, d-Bicuculline |
| Definition: | A benzylisoquinoline alkaloid that is 6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinoline which is substituted at the 5-pro-S position by a (6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl group. A light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. |
| Ontology: | ChEBI [CHEBI:3092] ( EBI ) |
| chemical treatment: tubocurarine |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | tubocurarine |
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| Synonyms: | (+)-tubocurarine, 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraran-2'-ium, 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraranium, d-tubocurarine, Tubocurarin, Tubocurarine |
| Definition: | A benzylisoquinoline alkaloid muscle relaxant which constitutes the active component of curare. |
| Ontology: | ChEBI [CHEBI:9774] ( EBI ) |
| chemical treatment: 6-Cyano-7-nitroquinoxaline-2,3-dione |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | 6-Cyano-7-nitroquinoxaline-2,3-dione |
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| Synonyms: | 6-Cyano-7-nitroquinoxaline-2,3-dione, CNQX |
| Definition: | |
| Ontology: | ChEBI [CHEBI:34468] ( EBI ) |
| chemical treatment: tetrodotoxin |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | tetrodotoxin |
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| Synonyms: | (1R,5R,6R,7R,9S,11R,12R,13S,14S)-14-(hydroxymethyl)-3-imino-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1(7,11).0(1,6)]tetradecane-5,9,12,13,14-pentol, Babylonia japonica toxin 1, BJT 1, fugu poison, maculotoxin, octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol, spheroidine, tarichatoxin, tetrodontoxin, Tetrodotoxin, tetrodotoxine, TTX |
| Definition: | A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels. |
| Ontology: | ChEBI [CHEBI:9506] ( EBI ) |
| Publication: | Hirata et al., 2013 |
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