| ZFIN ID: ZDB-EXP-090916-11 |
Experiment Conditions Description: chemical treatment: lovastatin, chemical treatment: mevalonate
| chemical treatment: lovastatin |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | lovastatin |
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| Synonyms: | (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate, (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate, 2beta,6alpha-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone, 6alpha-methylcompactin, Lovastatin, Mevacor, Mevinolin, MK-803, ML-530B |
| Definition: | A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom). |
| Ontology: | ChEBI [CHEBI:40303] ( EBI ) |
| chemical treatment: mevalonate |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | mevalonate |
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| Synonyms: | (+-)-mevalonate, (RS)-mevalonate, 3,5-dihydroxy-3-methylpentanoate, mevalonic acid anion, rac-3,5-dihydroxy-3-methylpentanoate, rac-mevalonate, racemic mevalonate, RS-mevalonate |
| Definition: | A racemate composed of equimolar amounts of (R)- and (S)-mevalonate. |
| Ontology: | ChEBI [CHEBI:25350] ( EBI ) |
| Publication: | Cao et al., 2009 |
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