| ZFIN ID: ZDB-EXP-080911-3 |
Experiment Conditions Description: radiation, chemical treatment: seliciclib
| radiation |
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| Name: | radiation |
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| Definition: | |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000208] |
| chemical treatment: seliciclib |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | seliciclib |
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| Synonyms: | (2R)-2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-1-butanol, (2R)-2-{[6-(benzylamino)-9-(1-methylethyl)-9H-purin-2-yl]amino}butan-1-ol, (2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol, (R)-2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-1-butanol, 2-(R)-(1-ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine, CYC202, R-Roscovitine, Roscovitine, seliciclib |
| Definition: | 2,6-Diaminopurine carrying benzylamino, (2R)-1-hydroxybutan-2-yl and isopropyl substituents at C-6, C-2-N and N-9 respectively. It is an experimental drug candidate in the family of pharmacological cyclin-dependent kinase (CDK) inhibitors. |
| Ontology: | ChEBI [CHEBI:45307] ( EBI ) |
| Publication: | Lee et al., 2008 |
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