| ZFIN ID: ZDB-EXP-050606-6 |
Experiment Conditions Description: chemical treatment: 17beta-estradiol, chemical treatment: fulvestrant
| chemical treatment: 17beta-estradiol |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | 17beta-estradiol |
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| Synonyms: | (17beta)-estra-1,3,5(10)-triene-3,17-diol, 17beta oestradiol, 17beta-estra-1,3,5(10)-triene-3,17-diol, 17beta-estradiol, 17beta-oestradiol, beta-Estradiol, cis-estradiol, estra-1,3,5(10)-triene-3,17beta-diol, Estradiol, Estradiol-17beta |
| Definition: | The 17beta-isomer of estradiol. |
| Ontology: | ChEBI [CHEBI:16469] ( EBI ) |
| chemical treatment: fulvestrant |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | fulvestrant |
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| Synonyms: | (7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diol, 7alpha-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17beta-diol, Faslodex, fulvestrant, fulvestrantum, ICI 182780, ICI-182780 |
| Definition: | A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer. |
| Ontology: | ChEBI [CHEBI:31638] ( EBI ) |
| Publication: | Menuet et al., 2005 |
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