ZFIN ID: ZDB-EXP-250303-1 |
Experiment Conditions Description: chemical treatment by environment: antalarmin
chemical treatment by environment: antalarmin |
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Name: | chemical treatment by environment |
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Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | antalarmin |
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Synonyms: | N-butyl-N-ethyl-7-mesityl-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
Definition: | A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidin-4-amine which is substituted by methyl groups at positions 2, 5, and 6, by a mesityl group at position 7, and in which the amino substituent at position 4 has been substituted by ethyl and butyl groups. It is an antagonist of corticotropin-releasing factor 1 (CRF-1) receptors (Ki = 1 nM). |
Ontology: | ChEBI [CHEBI:139557] ( EBI ) |
Publication: | Wagle et al., 2022 |
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