Transgenic Construct
Tg(sox10:irf6_R84C,myl7:EGFP)
- ID
- ZDB-TGCONSTRCT-130911-3
- Name
- Tg(sox10:irf6_R84C,myl7:EGFP)
- Previous Names
-
- Tg(sox10:irf6_R84C) (1)
- Type
- engineered_plasmid
- Regulatory Regions
- Coding Sequences
- [Em λ][Ex λ]
- Fpbase:EGFP
- Contains Sequences
- Note
-
This construct expresses dominant negative R84C irf6 under the control of the sox10 promoter. Created to model human IRF6 mutations in which arginine 84 plays a crucial role in DNA binding.
Reference: Dougherty et al. (2013)
Plasmid Map
None
Genomic Features
That Utilize Tg(sox10:irf6_R84C,myl7:EGFP) Construct
Genomic Feature | Affected Genomic Regions |
---|---|
zf394Tg |
Transgenics
That Utilize Tg(sox10:irf6_R84C,myl7:EGFP) Construct
Fish | Affected Genomic Regions | Phenotype | Gene Expression |
---|---|---|---|
zf394Tg |
|
Fig. 3 from Dougherty et al., 2013 |
Sequence Information
Other Construct Pages
None
Citations