TALEN

TALEN1-il1b

ID

ZDB-TALEN-230202-1

Name

TALEN1-il1b

Previous Names

None

Target

il1b (1)

Target Sequence 1

5' - CCCTGCAGAGCTACAG - 3'

Target Sequence 2

5' - CTCCAGCCTGATGCC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
phk2	il1b

Expression

Gene expression in Wild Types + TALEN1-il1b

No data available

Phenotype

Phenotype resulting from TALEN1-il1b

No data available

Phenotype of all Fish created by or utilizing TALEN1-il1b

Phenotype	Fish	Conditions	Figures
microglial cell lysosome decreased amount, abnormal	il1b^phk2/phk2	standard conditions	Fig. 6 from Chen et al., 2022
microglial cell lysosome decreased amount, abnormal	il1b^phk2/phk2	amputation: caudal fin	Fig. 6 from Chen et al., 2022
head cxcl8a expression decreased amount, abnormal	il1b^phk2/phk2	standard conditions	Fig. 2 from Chen et al., 2022
head macrophage normal amount, ameliorated	il1b^phk2/phk2	amputation: caudal fin	Fig. 2 from Chen et al., 2022
head hspa4b expression amount, ameliorated	il1b^phk2/phk2	amputation: caudal fin	Fig. 7 from Chen et al., 2022
head aifm4 expression amount, ameliorated	il1b^phk2/phk2	amputation: caudal fin	Fig. 7 from Chen et al., 2022
head camk2g1 expression decreased amount, abnormal	il1b^phk2/phk2	standard conditions	Fig. 7 from Chen et al., 2022
head apoeb expression decreased amount, abnormal	il1b^phk2/phk2	standard conditions	Fig. 7 from Chen et al., 2022
head apoeb expression decreased amount, abnormal	il1b^phk2/phk2	amputation: caudal fin	Fig. 7 from Chen et al., 2022
head hmgb1b expression decreased amount, abnormal	il1b^phk2/phk2	amputation: caudal fin	Fig. 7 from Chen et al., 2022
head psmd1 expression amount, ameliorated	il1b^phk2/phk2	amputation: caudal fin	Fig. 7 from Chen et al., 2022
head hmgb1b expression decreased amount, abnormal	il1b^phk2/phk2	standard conditions	Fig. 7 from Chen et al., 2022
head banf1 expression amount, ameliorated	il1b^phk2/phk2	amputation: caudal fin	Fig. 7 from Chen et al., 2022
brain apoptotic process normal occurrence, ameliorated	il1b^phk2/phk2	amputation: caudal fin	Fig. 5 from Chen et al., 2022
head il6 expression decreased amount, abnormal	il1b^phk2/phk2	standard conditions	Fig. 2 from Chen et al., 2022
brain leukocyte normal amount, ameliorated	il1b^phk2/phk2	amputation: caudal fin	Fig. 2 from Chen et al., 2022
head c3a.1 expression amount, ameliorated	il1b^phk2/phk2	amputation: caudal fin	Fig. 7 from Chen et al., 2022
head tnfa expression decreased amount, abnormal	il1b^phk2/phk2	standard conditions	Fig. 2 from Chen et al., 2022
head camk2g1 expression decreased amount, abnormal	il1b^phk2/phk2	amputation: caudal fin	Fig. 7 from Chen et al., 2022

Citations