TALEN

TALEN1-smarca4a

ID

ZDB-TALEN-210803-1

Name

TALEN1-smarca4a

Previous Names

None

Target

smarca4a (1)

Target Sequence 1

5' - CCTGGGGCCATGTTAGGGC - 3'

Target Sequence 2

5' - GCCATGGGCAGAGCCA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
hzu13	smarca4a

Expression

Gene expression in Wild Types + TALEN1-smarca4a

No data available

Phenotype

Phenotype resulting from TALEN1-smarca4a

No data available

Phenotype of all Fish created by or utilizing TALEN1-smarca4a

Phenotype	Fish	Conditions	Figures
whole organism klf2a expression decreased amount, abnormal	smarca4a^hzu13/hzu13	standard conditions	Fig. 3 from Tu et al., 2020
ventral wall of dorsal aorta hematopoietic stem cell normal amount, ameliorated	smarca4a^hzu13/hzu13	chemical treatment by environment: S-nitroso-N-acetyl-D-penicillamine	Fig. 3 from Tu et al., 2020
ventral wall of dorsal aorta hematopoietic stem cell decreased amount, abnormal	smarca4a^hzu13/hzu13	standard conditions	Fig. 3 from Tu et al., 2020
ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal	smarca4a^hzu13/hzu13	standard conditions	Fig. 2, Fig. 3 from Tu et al., 2020
ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression amount, ameliorated	smarca4a^hzu13/hzu13	chemical treatment by environment: S-nitroso-N-acetyl-D-penicillamine	Fig. 3 from Tu et al., 2020
whole organism nitric oxide normal amount, ameliorated	smarca4a^hzu13/hzu13	chemical treatment by environment: S-nitroso-N-acetyl-D-penicillamine	Fig. 3 from Tu et al., 2020
whole organism nitric oxide decreased amount, abnormal	smarca4a^hzu13/hzu13	standard conditions	Fig. 3 from Tu et al., 2020
whole organism runx1 expression decreased amount, abnormal	smarca4a^hzu13/hzu13	standard conditions	Fig. 2 from Tu et al., 2020
whole organism nos1 expression decreased amount, abnormal	smarca4a^hzu13/hzu13	standard conditions	Fig. 3 from Tu et al., 2020
whole organism smarca4a expression decreased amount, abnormal	smarca4a^hzu13/hzu13	standard conditions	Fig. 1, Fig. 3 from Tu et al., 2020
whole organism nos2b expression decreased amount, abnormal	smarca4a^hzu13/hzu13	standard conditions	Fig. 3 from Tu et al., 2020
ventral wall of dorsal aorta hematopoietic stem cell decreased amount, abnormal	smarca4a^hzu13/hzu13; is5Tg; zf289Tg	standard conditions	Fig. 2 from Tu et al., 2020
whole organism smarca4a expression decreased amount, abnormal	smarca4a^hzu13/hzu13; is5Tg; zf289Tg	standard conditions	Fig. 1 from Tu et al., 2020
caudal hematopoietic tissue hematopoietic stem cell normal amount, ameliorated	smarca4a^hzu13/hzu13; zf289Tg	chemical treatment by environment: S-nitroso-N-acetyl-D-penicillamine	Fig. 5 from Tu et al., 2020
caudal hematopoietic tissue hematopoietic stem cell apoptotic, ameliorated	smarca4a^hzu13/hzu13; zf289Tg	chemical treatment by environment: S-nitroso-N-acetyl-D-penicillamine	Fig. 5 from Tu et al., 2020
caudal hematopoietic tissue hematopoietic stem cell apoptotic, abnormal	smarca4a^hzu13/hzu13; zf289Tg	standard conditions	Fig. 5 from Tu et al., 2020
caudal hematopoietic tissue hematopoietic stem cell decreased amount, abnormal	smarca4a^hzu13/hzu13; zf289Tg	standard conditions	Fig. 5 from Tu et al., 2020

Citations