TALEN

TALEN1-shha

ID

ZDB-TALEN-170929-2

Name

TALEN1-shha

Previous Names

None

Target

shha (1)

Target Sequence 1

5' - AGACTATATCGTTTG - 3'

Target Sequence 2

5' - TCACTTCATTGTGTT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
vcc8Gt	shha

Expression

Gene expression in Wild Types + TALEN1-shha

No data available

Phenotype

Phenotype resulting from TALEN1-shha

No data available

Phenotype of all Fish created by or utilizing TALEN1-shha

Phenotype	Fish	Conditions	Figures
whole organism shha expression decreased amount, abnormal	shha^vcc8Gt/+; vcc9Tg/+ (EKW)	control	Fig. 3 S2 from Sugimoto et al., 2017
epicardium shha expression absent, abnormal	shha^{vcc8Gt/vcc8Gt}; pd37Tg/+; pd42Tg/+ (EKW)	amputation: cardiac ventricle, chemical treatment by environment: tamoxifen	Fig. 5 from Sugimoto et al., 2017
epicardium aldh1a2 expression absent, abnormal	shha^{vcc8Gt/vcc8Gt}; pd37Tg/+; pd42Tg/+ (EKW)	chemical treatment by environment: tamoxifen	Fig. 4 from Sugimoto et al., 2017
heart aldh1a2 expression decreased amount, abnormal	shha^{vcc8Gt/vcc8Gt}; pd42Tg/+ (EKW)	chemical treatment by environment: tamoxifen	Fig. 4 from Sugimoto et al., 2017
ventricular myocardium decreased thickness, abnormal	shha^{vcc8Gt/vcc8Gt}; pd42Tg/+ (EKW)	chemical treatment by environment: tamoxifen	Fig. 4 from Sugimoto et al., 2017
heart edematous, abnormal	shha^{vcc8Gt/vcc8Gt}; pd42Tg/+ (EKW)	chemical treatment by environment: tamoxifen	Fig. 4 from Sugimoto et al., 2017
heart shha expression absent, abnormal	shha^{vcc8Gt/vcc8Gt}; pd42Tg/+ (EKW)	chemical treatment by environment: tamoxifen	Fig. 4 from Sugimoto et al., 2017
heart fgf16 expression decreased amount, abnormal	shha^{vcc8Gt/vcc8Gt}; pd42Tg/+ (EKW)	chemical treatment by environment: tamoxifen	Fig. 4 from Sugimoto et al., 2017
regenerating tissue cardiac muscle cell proliferation decreased occurrence, abnormal	shha^{vcc8Gt/vcc8Gt}; pd42Tg/+ (EKW)	amputation: cardiac ventricle, chemical treatment by environment: tamoxifen	Fig. 5 from Sugimoto et al., 2017
heart ptch1 expression absent, abnormal	shha^{vcc8Gt/vcc8Gt}; pd42Tg/+ (EKW)	chemical treatment by environment: tamoxifen	Fig. 4 from Sugimoto et al., 2017
heart fgf2 expression decreased amount, abnormal	shha^{vcc8Gt/vcc8Gt}; pd42Tg/+ (EKW)	chemical treatment by environment: tamoxifen	Fig. 4 from Sugimoto et al., 2017
cardiac muscle cell decreased amount, abnormal	shha^{vcc8Gt/vcc8Gt}; pd42Tg/+ (EKW)	chemical treatment by environment: tamoxifen	Fig. 4 from Sugimoto et al., 2017
heart wnt9b expression decreased amount, abnormal	shha^{vcc8Gt/vcc8Gt}; pd42Tg/+ (EKW)	chemical treatment by environment: tamoxifen	Fig. 4 from Sugimoto et al., 2017
pectoral fin decreased size, abnormal	shha^{vcc8Gt/vcc8Gt}; vcc9Tg/+ (EKW)	standard conditions	Fig. 3 S2 from Sugimoto et al., 2017
whole organism shha expression absent, abnormal	shha^{vcc8Gt/vcc8Gt}; vcc9Tg/+ (EKW)	control	Fig. 3 S2 from Sugimoto et al., 2017

Citations