TALEN

TALEN1-ahi1

ID

ZDB-TALEN-170314-2

Name

TALEN1-ahi1

Previous Names

None

Target

ahi1 (1)

Target Sequence 1

5' - TGTCAGCAGAAAACCAGACAG - 3'

Target Sequence 2

5' - TCCTCCTTGAACTCCTCTACA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
lri46	ahi1
lri47	ahi1
lri53	ahi1

Expression

Gene expression in Wild Types + TALEN1-ahi1

No data available

Phenotype

Phenotype resulting from TALEN1-ahi1

No data available

Phenotype of all Fish created by or utilizing TALEN1-ahi1

Phenotype	Fish	Conditions	Figures
post-vent region curved ventral, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 1 from Lessieur et al., 2017
retinal cone cell has fewer parts of type retinal cone cell photoreceptor outer segment, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 4 from Lessieur et al., 2017
whole organism lacks all parts of type swim bladder, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 1 from Lessieur et al., 2017
retinal outer nuclear layer dorsal region decreased thickness, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 4 from Lessieur et al., 2017
photoreceptor outer segment layer dorsal region malformed, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 4 from Lessieur et al., 2017
retinal cone cell photoreceptor cell outer segment organization decreased process quality, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 3 , Fig. 4 , Fig. 5 , Fig. 7 from Lessieur et al., 2017
posterior pronephric duct lacks all parts of type posterior pronephric duct motile cilium, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 2 from Lessieur et al., 2017
retinal cone cell development decreased process quality, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 3 , Fig. 7 from Lessieur et al., 2017
retinal cone cell lacks all parts of type retinal cone cell photoreceptor outer segment, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 7 from Lessieur et al., 2017
pronephric duct cilium assembly decreased occurrence, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 2 from Lessieur et al., 2017
retinal cone cell photoreceptor outer segment irregular spatial pattern, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 3 from Lessieur et al., 2017
retinal cone cell photoreceptor disc membrane irregular spatial pattern, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 5 from Lessieur et al., 2017
retinal outer nuclear layer zpr-3 labeling mislocalised, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 6 from Lessieur et al., 2017
retinal cone cell photoreceptor outer segment decreased length, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 3 , Fig. 5 , Fig. 7 from Lessieur et al., 2017
retinal cone cell photoreceptor outer segment disorganized, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 3 , Fig. 5 from Lessieur et al., 2017
eye photoreceptor cell photoreceptor connecting cilium cc2d2a expression decreased amount, abnormal	ahi1^lri46/lri46	standard conditions	Fig. 9 from Lessieur et al., 2017
retinal cone cell cone photoreceptor outer segment decreased amount, abnormal	cep290^fh297/fh297; ahi1^lri46/+	standard conditions	Fig 9 from Lessieur et al., 2019
optokinetic behavior decreased process quality, abnormal	cep290^fh297/fh297; ahi1^lri46/+	standard conditions	Fig. 12 from Lessieur et al., 2019
retinal cone cell decreased amount, abnormal	cep290^fh297/fh297; ahi1^lri46/+	standard conditions	Fig 9 from Lessieur et al., 2019
photoreceptor inner segment layer zpr-3 labeling mislocalised, abnormal	cep290^fh297/fh297; ahi1^lri46/+	standard conditions	Fig 9 from Lessieur et al., 2019
optokinetic behavior decreased process quality, abnormal	cep290^fh297/fh297; ahi1^lri46/lri46	standard conditions	Fig. 12 from Lessieur et al., 2019
whole organism decreased life span, abnormal	cep290^fh297/fh297; ahi1^lri46/lri46	standard conditions	text only from Lessieur et al., 2019
whole organism dead, abnormal	cep290^fh297/fh297; ahi1^lri46/lri46	standard conditions	text only from Lessieur et al., 2019

Citations