TALEN

TALEN1-il2rga

ID

ZDB-TALEN-160527-1

Name

TALEN1-il2rga

Previous Names

None

Target

il2rga (1)

Target Sequence 1

5' - TGGCAGTTTGGTGACGGAAC - 3'

Target Sequence 2

5' - TTCTCATACCATATTCTTTC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
mdu1	il2rga
mdu2	il2rga
mdu3	il2rga
mdu4	il2rga

Expression

Gene expression in Wild Types + TALEN1-il2rga

No data available

Phenotype

Phenotype resulting from TALEN1-il2rga

No data available

Phenotype of all Fish created by or utilizing TALEN1-il2rga

Phenotype	Fish	Conditions	Figures
thymus rag1 expression decreased distribution, abnormal	il2rga^mdu1/mdu1	standard conditions	Figure 1 from Sertori et al., 2022
kidney cd79a expression increased amount, abnormal	il2rga^mdu2/mdu2	standard conditions	Figure 2 from Sertori et al., 2022
kidney common myeloid progenitor increased amount, abnormal	il2rga^mdu2/mdu2	standard conditions	Figure 2 from Sertori et al., 2022
kidney nkl.3 expression decreased amount, abnormal	il2rga^mdu2/mdu2	standard conditions	Figure 2 from Sertori et al., 2022
thymus rag1 expression decreased distribution, abnormal	il2rga^mdu2/mdu2	standard conditions	Figure 1 from Sertori et al., 2022
thymus T cell trac expression decreased distribution, abnormal	il2rga^mdu2/mdu2	standard conditions	Figure 1 from Sertori et al., 2022
kidney lymphocyte decreased amount, abnormal	il2rga^mdu2/mdu2	standard conditions	Figure 2 from Sertori et al., 2022
kidney trac expression decreased amount, abnormal	il2rga^mdu2/mdu2	standard conditions	Figure 2 from Sertori et al., 2022
kidney cd4-1 expression decreased amount, abnormal	il2rga^mdu2/mdu2	standard conditions	Figure 2 from Sertori et al., 2022
thymus T cell lck expression decreased distribution, abnormal	il2rga^mdu2/mdu2	standard conditions	Figure 1 from Sertori et al., 2022
blood neutrophil increased amount, abnormal	il2rga^mdu2/mdu2	standard conditions	Figure 2 from Sertori et al., 2022
blood lymphocyte decreased amount, abnormal	il2rga^mdu2/mdu2	standard conditions	Figure 2 from Sertori et al., 2022
thymus rag1 expression decreased distribution, abnormal	il2rga^mdu3/mdu3	standard conditions	Figure 1 from Sertori et al., 2022
thymus rag1 expression decreased distribution, abnormal	il2rga^mdu4/mdu4	standard conditions	Figure 1 from Sertori et al., 2022
thymus T cell trac expression decreased distribution, abnormal	il2rga^mdu4/mdu4	standard conditions	Figure 1 from Sertori et al., 2022
thymus T cell lck expression decreased distribution, abnormal	il2rga^mdu4/mdu4	standard conditions	Figure 1 from Sertori et al., 2022
thymus rag1 expression decreased amount, abnormal	il2rga^mdu4/+; il2rga^mdu2/+	standard conditions	Fig. S2 from Sertori et al., 2016
mature B cell decreased amount, abnormal	il2rga^mdu4/+; il2rga^mdu2/+	standard conditions	Fig. 2 from Sertori et al., 2016
T cell absent, abnormal	il2rga^mdu4/+; il2rga^mdu2/+	standard conditions	Fig. 2 from Sertori et al., 2016

Citations