TALEN

TALEN1-tet3

ID
ZDB-TALEN-151217-5
Name
TALEN1-tet3
Previous Names
None
Target
Target Sequence 1
5' - TGACCGCACTCACCCA - 3'
Target Sequence 2
5' - TTCTTGTGCTGGTAGAAGAC - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
mk18 tet3
Expression
Gene expression in Wild Types + TALEN1-tet3
No data available
Phenotype
Phenotype resulting from TALEN1-tet3
No data available
Phenotype of all Fish created by or utilizing TALEN1-tet3
Phenotype Fish Conditions Figures
eye gnb3a expression decreased amount, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 3 from Gore et al., 2018
brain morphology, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 1 with image from Li et al., 2015
trunk curved, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 1 with image from Li et al., 2015
whole organism decreased life span, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions text only from Gore et al., 2018
trunk gata2b expression decreased amount, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 6 with image from Li et al., 2015
atrioventricular canal bmp4 expression absent, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 4 with imageFig. 5 with image from Lan et al., 2019
eye decreased size, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 3 from Gore et al., 2018
Fig. 1 with image from Li et al., 2015
thymus T cell rag1 expression absent, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 3 with image from Li et al., 2015
heart chromosomal 5-methylcytosine DNA demethylation pathway decreased process quality, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 3Fig. 5 with image from Lan et al., 2019
dorsal aorta runx1 expression decreased amount, abnormal tet2mk17/mk17; tet3mk18/mk18 control Fig. 6 with image from Li et al., 2015
dorsal aorta tal1 expression decreased amount, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 6 with image from Li et al., 2015
dorsal aorta hematopoietic stem cell runx1 expression decreased amount, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 3 with image from Li et al., 2015
dorsal aorta hematopoietic stem cell myb expression decreased amount, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 3 with image from Li et al., 2015
hematopoietic stem cell differentiation decreased process quality, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 3 with image from Li et al., 2015
eye DNA-methyltransferase activity increased occurrence, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 3 from Gore et al., 2018
proepicardial cluster wt1a expression decreased distribution, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 1 with image from Lan et al., 2019
eye crx expression decreased amount, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 3 from Gore et al., 2018
brain development disrupted, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions text only from Gore et al., 2018
pigmentation process quality, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 1 with image from Li et al., 2015
atrioventricular canal has2 expression absent, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 4 with imageFig. 5 with image from Lan et al., 2019
proepicardial cluster wt1a expression decreased amount, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 1 with image from Lan et al., 2019
heart inhbaa expression absent, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 5 with image from Lan et al., 2019
heart sox9b expression decreased amount, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 5 with image from Lan et al., 2019
atrioventricular canal vcana expression absent, abnormal tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 6 with image from Lan et al., 2019
atrioventricular canal endocardium GFP expression absent, abnormal tet2mk17/mk17; tet3mk18/mk18; ia4Tg standard conditions Fig. 4 with image from Lan et al., 2019
Wnt signaling pathway involved in heart development decreased process quality, abnormal tet2mk17/mk17; tet3mk18/mk18; ia4Tg standard conditions Fig. 4 with image from Lan et al., 2019
macrophage EGFP expression absent, abnormal tet2mk17/mk17; tet3mk18/mk18; nz117Tg standard conditions Fig. 3 with image from Li et al., 2015
neutrophil EGFP expression absent, abnormal tet2mk17/mk17; tet3mk18/mk18; nz117Tg standard conditions Fig. 3 with image from Li et al., 2015
proepicardium cell migration involved in pericardium morphogenesis disrupted, abnormal tet2mk17/mk17; tet3mk18/mk18; pd41Tg standard conditions Fig. 1 with image from Lan et al., 2019
proepicardial cluster EGFP expression mislocalised, abnormal tet2mk17/mk17; tet3mk18/mk18; pd41Tg standard conditions Fig. 1 with image from Lan et al., 2019
proepicardium cell migration involved in pericardium morphogenesis decreased occurrence, abnormal tet2mk17/mk17; tet3mk18/mk18; pd41Tg standard conditions Fig. 1 with image from Lan et al., 2019
proepicardium cell migration involved in pericardium morphogenesis occurrence, ameliorated tet2mk17/mk17; tet3mk18/mk18; pd41Tg chemical treatment by environment: 5-aza-2'-deoxycytidine Fig. 1 with image from Lan et al., 2019
atrioventricular valve absent, abnormal tet2mk17/mk17; tet3mk18/mk18; ubs1Tg standard conditions Fig. 4 with image from Lan et al., 2019
dorsal aorta ventral region EGFP expression decreased amount, abnormal tet2mk17/mk17; tet3mk18/mk18; um14Tg standard conditions Fig. 7 with image from Li et al., 2015
brain morphology, abnormal tet1mk16/mk16; tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 1 with image from Li et al., 2015
eye decreased size, abnormal tet1mk16/mk16; tet2mk17/mk17; tet3mk18/mk18 standard conditions Fig. 1 with image from Li et al., 2015
dorsal aorta nucleus broken, abnormal tet2mk17/mk17; tet3mk18/mk18; mu122Tg; s896Tg standard conditions Fig. 5 with image from Li et al., 2015
endothelial to hematopoietic transition decreased occurrence, abnormal tet2mk17/mk17; tet3mk18/mk18; mu122Tg; s896Tg standard conditions Fig. 5 with image from Li et al., 2015
Citations