TALEN

TALEN1-pllp

ID

ZDB-TALEN-150603-1

Name

TALEN1-pllp

Previous Names

None

Target

pllp (1)

Target Sequence 1

5' - TGACATGGGTTTTAT - 3'

Target Sequence 2

5' - CGGCTATAAGCAGTA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

designed to target the following sequence of Danio rerio pllp exon 1: 5'-TTGACATGGGTTTTATcaagagcattcctggaaTACTGCTTATAGCCGA-3', and composed of the following TAL effector domains: pCS2-TAL3DD_pllpE1 NG NN NI HD NI NG NN NN NN NG NG NG NG NI NG; pCS2-TAL3RR_pllpE1 HD NN NN HD NG NI NG NI NI NN HD NI NN NG NI.

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
pd1116	pllp

Expression

Gene expression in Wild Types + TALEN1-pllp

No data available

Phenotype

Phenotype resulting from TALEN1-pllp

No data available

Phenotype of all Fish created by or utilizing TALEN1-pllp

Phenotype	Fish	Conditions	Figures
intestinal epithelium Notch signaling pathway decreased process quality, abnormal	pllp^{pd1116/pd1116}	standard conditions	Fig. 6 from Rodríguez-Fraticelli et al., 2015
intestinal epithelial cell differentiation process quality, abnormal	pllp^{pd1116/pd1116}	standard conditions	Fig. 6 from Rodríguez-Fraticelli et al., 2015
intestinal epithelium has extra parts of type goblet cell, abnormal	pllp^{pd1116/pd1116}	standard conditions	Fig. 6 from Rodríguez-Fraticelli et al., 2015
intestinal epithelium has fewer parts of type enterocyte, abnormal	pllp^{pd1116/pd1116}	standard conditions	Fig. 6 from Rodríguez-Fraticelli et al., 2015
enterocyte differentiation decreased occurrence, abnormal	pllp^{pd1116/pd1116}	standard conditions	Fig. 6 from Rodríguez-Fraticelli et al., 2015
enterocyte recycling endosome mislocalised radially, abnormal	pllp^{pd1116/pd1116}	standard conditions	Fig. 2 from Rodríguez-Fraticelli et al., 2015
digestive tract morphogenesis decreased process quality, abnormal	pllp^{pd1116/pd1116}	standard conditions	Fig. 2 from Rodríguez-Fraticelli et al., 2015
intestinal epithelium epithelial cell decreased height, abnormal	pllp^{pd1116/pd1116}	standard conditions	Fig. 2 from Rodríguez-Fraticelli et al., 2015
intestinal epithelium malformed, abnormal	pllp^{pd1116/pd1116}	standard conditions	Fig. 2 from Rodríguez-Fraticelli et al., 2015
intestinal epithelium endocytosis decreased occurrence, abnormal	pllp^{pd1116/pd1116}	standard conditions	Fig. 2 from Rodríguez-Fraticelli et al., 2015
intestinal epithelium apical region physical object quality, abnormal	pllp^{pd1116/pd1116}	standard conditions	Fig. 5 from Rodríguez-Fraticelli et al., 2015
intestinal epithelium apical plasma membrane increased area, abnormal	pllp^{pd1116/pd1116}	standard conditions	Fig. 2 from Rodríguez-Fraticelli et al., 2015
intestinal epithelium endocytosis process quality, abnormal	pllp^{pd1116/pd1116}	standard conditions	Fig. 5 from Rodríguez-Fraticelli et al., 2015

Citations