PUBLICATION

Transcripts within rod photoreceptors of the Zebrafish retina

Authors
Sun, C., Galicia, C., Stenkamp, D.L.
ID
ZDB-PUB-180210-2
Date
2018
Source
BMC Genomics   19: 127 (Journal)
Registered Authors
Stenkamp, Deborah L.
Keywords
RNA-Seq, Regeneration, Retina, Rod photoreceptor, Transcriptome, Zebrafish
Datasets
GEO:GSE100062
MeSH Terms
  • Animals
  • Zebrafish/genetics*
  • Retinal Rod Photoreceptor Cells/metabolism*
  • High-Throughput Nucleotide Sequencing
  • Transcriptome*
  • Molecular Sequence Annotation
  • Computational Biology/methods
  • Gene Expression Profiling
  • Gene Library
  • Fluorescent Antibody Technique
  • Regeneration
  • Retina/cytology*
  • Retina/metabolism
  • Retina/pathology
  • Gene Ontology
  • Retinal Degeneration/genetics
  • Retinal Degeneration/metabolism
  • Retinal Degeneration/pathology
PubMed
29422031 Full text @ BMC Genomics
Abstract
The purpose of this study was to identify transcripts of retinal rod photoreceptors of the zebrafish. The zebrafish is an important animal model for vision science due to rapid and tractable development, persistent neurogenesis of rods throughout the lifespan, and capacity for functional retinal regeneration.
Zebrafish rods, and non-rod retinal cells of the xops:eGFP transgenic line, were separated by cell dissociation and fluorescence-activated cell sorting (FACS), followed by RNA-seq. At a false discovery rate of
We report the generation and validation of an RNA-seq dataset describing the rod transcriptome of the zebrafish, which is now available as a resource for further studies of rod photoreceptor biology and comparative transcriptomics.
Genes / Markers
Figures
Show all Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping