PUBLICATION
Xenopus laevis Nkx5.3 and sensory organ homeobox (SOHo) are expressed in developing sensory organs and ganglia of the head and anterior trunk
- Authors
- Kelly, L.E., El-Hodiri, H.M.
- ID
- ZDB-PUB-160710-3
- Date
- 2016
- Source
- Development genes and evolution 226(6): 423-428 (Journal)
- Registered Authors
- Keywords
- Cranial ganglia, Lateral line, Nkx5.3, Retina, Sensory organ homeobox, Xenopus laevis
- MeSH Terms
-
- Amino Acid Sequence
- Animals
- Ganglia/metabolism
- Homeodomain Proteins/chemistry
- Homeodomain Proteins/genetics
- Homeodomain Proteins/metabolism*
- In Situ Hybridization
- Nerve Tissue Proteins/chemistry
- Nerve Tissue Proteins/genetics
- Nerve Tissue Proteins/metabolism*
- Phylogeny
- Sense Organs/growth & development*
- Sense Organs/metabolism
- Sequence Alignment
- Transcription Factors/chemistry
- Transcription Factors/genetics
- Transcription Factors/metabolism*
- Xenopus Proteins/chemistry
- Xenopus Proteins/genetics
- Xenopus Proteins/metabolism*
- Xenopus laevis/anatomy & histology
- Xenopus laevis/growth & development*
- Xenopus laevis/metabolism
- PubMed
- 27392729 Full text @ Dev. Genes Evol.
Citation
Kelly, L.E., El-Hodiri, H.M. (2016) Xenopus laevis Nkx5.3 and sensory organ homeobox (SOHo) are expressed in developing sensory organs and ganglia of the head and anterior trunk. Development genes and evolution. 226(6):423-428.
Abstract
Nkx5 family members are homeobox transcription factors important for sensory organ development. Several members of the Nkx5 family are expressed in the eye, brain, developing ear, and lateral line. Members of this family have been previously identified in medaka, chick, and mouse. Here, we characterize two members of the Nkx5 family, Nkx5.3 and SOHo, in Xenopus laevis. We verify the identity of X. laevis Nkx5.3 and SOHo by phylogenetic comparison to chicken, medaka, and zebrafish orthologs. Both Nkx5.3 and SOHo are expressed in the developing eye, ear, lateral line system, and cranial neurons as determined by in situ hybridization.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping