PUBLICATION

Transcriptome analysis of Rpl11-deficient zebrafish model of Diamond-Blackfan Anemia

Authors
Zhang, Z., Jia, H., Zhang, Q., Wan, Y., Song, B., Jia, Q., Liu, H., Zhu, X., Fang, X.
ID
ZDB-PUB-151021-8
Date
2014
Source
Genomics Data   2: 173-5 (Journal)
Registered Authors
Jia, Haibo, Wang, Yang
Keywords
DBA, High-Seq 2000, IPA, Transcriptome, Zebrafish
Datasets
GEO:GSE51326
MeSH Terms
none
PubMed
26484089 Full text @ Genom. Data
Abstract
To comprehensively reflect the roles of Rpl11 on the transcriptome of zebrafish model of Diamond-Blackfan Anemia (DBA), we performed whole-genome transcriptome sequencing on the Illumina Hi-Seq 2000 sequencing platform. Two different transcriptomes of zebrafish Rpl11-deficient and control Morpholino (Mo) embryos were collected and analyzed. The experimental design and methods, including sample preparation, RNA-Seq data evaluation and treatment, were described in details so that representative high-throughput sequencing data were acquired for assessing the actual impacts of Rpl11 on zebrafish embryos. We provided the accession number GSE51326 for easy access to the database.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping