PUBLICATION
Dynamic expression of neurexophilin1 during zebrafish embryonic development
- Authors
- Thomas-Jinu, S., and Houart, C.
- ID
- ZDB-PUB-130806-6
- Date
- 2013
- Source
- Gene expression patterns : GEP 13(8): 395-401 (Journal)
- Registered Authors
- Houart, Corinne
- Keywords
- neuroexophilins, synapses, neurexins, epiphysis, zebrafish, interneurons, neurons
- MeSH Terms
-
- Brain/cytology
- Brain/embryology
- Brain/metabolism
- Animals
- Amino Acid Sequence
- Gene Expression*
- Spinal Cord/cytology
- Spinal Cord/embryology
- Spinal Cord/metabolism
- Sequence Homology, Amino Acid
- Glycoproteins/genetics
- Glycoproteins/metabolism*
- Zebrafish Proteins/genetics
- Zebrafish Proteins/metabolism*
- Phylogeny
- Interneurons/metabolism
- Embryonic Development
- Neuroglia/metabolism
- Organ Specificity
- Molecular Sequence Data
- Gene Expression Regulation, Developmental
- Zebrafish/embryology
- Zebrafish/metabolism*
- Neuropeptides/genetics
- Neuropeptides/metabolism*
- PubMed
- 23880144 Full text @ Gene Expr. Patterns
Citation
Thomas-Jinu, S., and Houart, C. (2013) Dynamic expression of neurexophilin1 during zebrafish embryonic development. Gene expression patterns : GEP. 13(8):395-401.
Abstract
Neurexophilin 1 (Nxph1) is a specific endoligand of α-neurexins that is essential for trans-synaptic activation. Here, we report its dynamic expression during development in zebrafish. Our study revealed an early onset of expression of nxph1. RT-PCR on a series of embryonic stages showed that it is maternally deposited, although only readily detectable by whole mount in situ hybridization by 22 hpf. During embryogenesis and larval stages, the zygotic transcript is expressed dynamically in various clusters of post-mitotic neurons and in glia in the central nervous system.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping