PUBLICATION
Allometric growth of the trunk leads to the rostral shift of the pelvic fin in teleost fishes
- Authors
- Murata, Y., Tamura, M., Aita, Y., Fujimura, K., Murakami, Y., Okabe, M., Okada, N., and Tanaka, M.
- ID
- ZDB-PUB-100811-8
- Date
- 2010
- Source
- Developmental Biology 347(1): 236-245 (Journal)
- Registered Authors
- Tanaka, Mikiko
- Keywords
- fin/limb position, zebrafish, cichlid, pelvic fin, Hox
- MeSH Terms
-
- Animal Structures/cytology
- Animal Structures/embryology*
- Animals
- Body Patterning*/genetics
- Cichlids/embryology*
- Cichlids/genetics
- Embryo, Nonmammalian/cytology
- Embryo, Nonmammalian/metabolism
- Gene Expression Regulation, Developmental
- Growth Differentiation Factors/genetics
- Growth Differentiation Factors/metabolism
- Mesoderm/cytology
- Mesoderm/embryology
- Models, Biological
- Motor Neurons/cytology
- Motor Neurons/metabolism
- Muscles/innervation
- Muscles/metabolism
- Pelvis/embryology*
- Pelvis/innervation
- Zebrafish/embryology*
- Zebrafish/genetics
- PubMed
- 20692249 Full text @ Dev. Biol.
Citation
Murata, Y., Tamura, M., Aita, Y., Fujimura, K., Murakami, Y., Okabe, M., Okada, N., and Tanaka, M. (2010) Allometric growth of the trunk leads to the rostral shift of the pelvic fin in teleost fishes. Developmental Biology. 347(1):236-245.
Abstract
The pelvic fin position among teleost fishes has shifted rostrally during evolution, resulting in diversification of both behavior and habitat. We explored the developmental basis for the rostral shift in pelvic fin position in teleost fishes using zebrafish (abdominal pelvic fins) and Nile tilapia (thoracic pelvic fins). Cell fate mapping experiments revealed that changes in the distribution of lateral plate mesodermal cells accompany the trunk-tail protrusion. Presumptive pelvic fin cells are originally located at the body wall adjacent to the anterior limit of hoxc10a expression in the spinal cord, and their position shifts rostrally as the trunk grows. We then showed that the differences in pelvic fin position between zebrafish and Nile tilapia were not due to changes in expression or function of gdf11. We also found that hox-independent motoneurons located above the pelvic fins innervate into the pelvic musculature. Our results suggest that there is a common mechanism among teleosts and tetrapods that controls paired appendage positioning via gdf11, but in teleost fishes the position of prospective pelvic fin cells on the yolk surface shifts as the trunk grows. In addition, teleost motoneurons, which lack lateral motor columns, innervate the pelvic fins in a manner independent of the rostral-caudal patterns of hox expression in the spinal cord.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping