PUBLICATION
Linker histone H1M transcripts mark the developing germ line in zebrafish
- Authors
- Wibrand, K. and Olsen, L.
- ID
- ZDB-PUB-020912-4
- Date
- 2002
- Source
- Mechanisms of Development 117(1-2): 249-252 (Journal)
- Registered Authors
- Keywords
- primordial germ cells; linker histone H1M; vasa; zebrafish; gene regulation; chromatin structure
- MeSH Terms
-
- Animals
- Base Sequence
- DNA, Complementary/genetics
- Gene Expression Regulation, Developmental
- Germ Cells/metabolism
- Histones/genetics*
- In Situ Hybridization
- RNA, Messenger/genetics
- RNA, Messenger/metabolism
- Zebrafish/embryology*
- Zebrafish/genetics*
- Zebrafish/metabolism
- Zebrafish Proteins/genetics*
- PubMed
- 12204265 Full text @ Mech. Dev.
Citation
Wibrand, K. and Olsen, L. (2002) Linker histone H1M transcripts mark the developing germ line in zebrafish. Mechanisms of Development. 117(1-2):249-252.
Abstract
Maternally synthesised factors contribute to the establishment of the germ cell lineage in lower vertebrates. In zebrafish, germ-soma segregation appears to be completed by the late blastula stage of development. To search for new germ cell factors in the zebrafish, we have used subtractive cDNA cloning. Here we report that linker histone H1M transcripts mark the germ line from the early gastrulation up to 18h post-fertilisation.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping