PUBLICATION
The zygotic expression of zebrafish trebf during embryogenesis is restricted to the embryonic shield and its derivatives
- Authors
- Liang, L.Y., Li, M., Wang, Y., Zhao, C.T., Zhao, Z.X., and Meng, A.M.
- ID
- ZDB-PUB-011108-5
- Date
- 2001
- Source
- Development genes and evolution 211(8-9): 445-448 (Journal)
- Registered Authors
- Meng, Anming, Wang, Yihong
- Keywords
- zebrafish; Trebf; hatching gland; notochord
- MeSH Terms
-
- Amino Acid Sequence
- Animals
- Conserved Sequence
- DNA-Binding Proteins/chemistry
- Embryonic Structures/metabolism*
- Gene Expression Profiling
- Gene Expression Regulation, Developmental
- Humans
- Mice
- Molecular Sequence Data
- RNA, Messenger/genetics
- RNA, Messenger/metabolism
- Sequence Homology, Amino Acid
- Transcription Factors/chemistry
- Zebrafish/anatomy & histology
- Zebrafish/embryology*
- Zebrafish/genetics*
- Zebrafish Proteins/chemistry
- Zebrafish Proteins/genetics*
- PubMed
- 11685580 Full text @ Dev. Genes Evol.
Citation
Liang, L.Y., Li, M., Wang, Y., Zhao, C.T., Zhao, Z.X., and Meng, A.M. (2001) The zygotic expression of zebrafish trebf during embryogenesis is restricted to the embryonic shield and its derivatives. Development genes and evolution. 211(8-9):445-448.
Abstract
We have identified a zebrafish gene trebf that shows an overall similarity of 51.5% and 55.1% in amino acid sequence with human and mouse TREB5/hXBP-1/HTF, respectively. Northern hybridization reveals that trebf mRNA is expressed throughout the life cycle of zebrafish. Whole-mount in situ hybridization detects an expression pattern of trebf in zebrafish that is very different from that of mammalian TREB5. Just before the onset of gastrulation, trebf transcripts are accumulated in the dorsal blastoderm margin and subsequently in the forming organizer. During gastrulation, the trebf-positive cells in the organizer migrate toward the animal pole and form two distinct domains. The cells in the anterior leading expression domain ultimately differentiate into hatching gland, whereas those in the following domain form the notochord.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping