Person
Wang, Qiang
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Biography and Research Interest
Dr. Qiang Wang
Born: November 1, 1975 in China.
professor in School of Medicine, South China University of Technology, Guangzhou, 510006, China
Tel: 86-20-39380943 (lab)
E-mail: qiangwang@scut.edu.cn
Dr. Wang is professor at School of Medicine, South China University of Technology, and he is a recipient of National Science Fund for Excellent Young Scholars. Dr. Wang mainly works on signal transduction regulation,and has made significant progress in elucidating the regulation mechanism of TGF-β superfamily signaling during early embryo development and tissue formation. The related papers were published on the famous international academic journals such as Developmental Cell, Blood, Molecular and Cellular Biology, J Biol.Chem. etc.
EDUCATION
Postdoctoral fellowship in Molecular Cell Biology Lab, Departement of Biological Sciences and Biotechnology, Tsinghua Unversity, Beijing, P. R. China, July, 2004~2008.
Ph.D. in Lab of Developmental Immunology, College of Life Science, Shandong University, Shandong province, P. R. China, 1999～2004 (Major thesis research done in Pathology Department, Peking Univeristy Health Science Centre, November, 2001~ March, 2004).
B.S. in Biological Science, College of Life Science, Shandong University, Shandong province, Beijing, P. R. China, 1999.
WORK EXPERIENCE
Associate professor in the Institute of Zoology, Chinese Academy of Sciences, 2008~2012, Beijing, P. R. China
Professor in the Institute of Zoology, Chinese Academy of Sciences, 2013~2022, Beijing, P. R. China
Professor in School of Medicine, South China University of Technology, 2022~Present, Guangzhou, P.R.China,
MAIN RESEARCH FIELDS:
The basic body plan of vertebrate embryos is established during embryo morphogenesis. How a relatively uniform embryo becomes asymmetric at the early developmental stages? This asymmetry consists of two aspects, the initial cell fate decision and the embryonic body patterning that establishes the dorsal-ventral, anterior-posterior, and left-right axes. Understanding the underlying molecular genetic mechanisms of these morphogenetic processes is one of the central goals of developmental biology. The function of genes and signal pathways, such as TGF-β, BMP and Wnt, are being studied in zebrafish embryos and mammalian cell lines using genetic, biochemical and molecular approaches. Research progresses on the great mysteries during embryo morphogenesis will help us to get a better understanding of how a fertilized egg gives rise to a live baby.
Born: November 1, 1975 in China.
professor in School of Medicine, South China University of Technology, Guangzhou, 510006, China
Tel: 86-20-39380943 (lab)
E-mail: qiangwang@scut.edu.cn
Dr. Wang is professor at School of Medicine, South China University of Technology, and he is a recipient of National Science Fund for Excellent Young Scholars. Dr. Wang mainly works on signal transduction regulation,and has made significant progress in elucidating the regulation mechanism of TGF-β superfamily signaling during early embryo development and tissue formation. The related papers were published on the famous international academic journals such as Developmental Cell, Blood, Molecular and Cellular Biology, J Biol.Chem. etc.
EDUCATION
Postdoctoral fellowship in Molecular Cell Biology Lab, Departement of Biological Sciences and Biotechnology, Tsinghua Unversity, Beijing, P. R. China, July, 2004~2008.
Ph.D. in Lab of Developmental Immunology, College of Life Science, Shandong University, Shandong province, P. R. China, 1999～2004 (Major thesis research done in Pathology Department, Peking Univeristy Health Science Centre, November, 2001~ March, 2004).
B.S. in Biological Science, College of Life Science, Shandong University, Shandong province, Beijing, P. R. China, 1999.
WORK EXPERIENCE
Associate professor in the Institute of Zoology, Chinese Academy of Sciences, 2008~2012, Beijing, P. R. China
Professor in the Institute of Zoology, Chinese Academy of Sciences, 2013~2022, Beijing, P. R. China
Professor in School of Medicine, South China University of Technology, 2022~Present, Guangzhou, P.R.China,
MAIN RESEARCH FIELDS:
The basic body plan of vertebrate embryos is established during embryo morphogenesis. How a relatively uniform embryo becomes asymmetric at the early developmental stages? This asymmetry consists of two aspects, the initial cell fate decision and the embryonic body patterning that establishes the dorsal-ventral, anterior-posterior, and left-right axes. Understanding the underlying molecular genetic mechanisms of these morphogenetic processes is one of the central goals of developmental biology. The function of genes and signal pathways, such as TGF-β, BMP and Wnt, are being studied in zebrafish embryos and mammalian cell lines using genetic, biochemical and molecular approaches. Research progresses on the great mysteries during embryo morphogenesis will help us to get a better understanding of how a fertilized egg gives rise to a live baby.
Non-Zebrafish Publications
[1] Y. Li, X. Kang, and Q. Wang*, HSP70 decreases receptor-dependent phosphorylation of Smad2 and blocks TGF-beta-induced epithelial-mesenchymal transition. J Genet Genomics 38 (2011) 111-116. (Corresponding author)
[2] W. Zhang, Y. Jiang, Q. Wang, X. Ma, Z. Xiao, W. Zuo, X. Fang, and Y.G. Chen, Single-molecule imaging reveals transforming growth factor-beta-induced type II receptor dimerization. Proc Natl Acad Sci U S A 106 (2009) 15679-15683.
[3] Q. Wang, Z. Huang, H. Xue, C. Jin, X.L. Ju, J.D. Han, and Y.G. Chen, MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4. Blood 111 (2008) 588-595.
[4] J. Yu, Q. Wang, X. Shi, X. Ma, H. Yang, Y.G. Chen, and X. Fang, Single-molecule force spectroscopy study of interaction between transforming growth factor beta1 and its receptor in living cells. J Phys Chem B 111 (2007) 13619-13625.
[5] X. Ma, Q. Wang, Y. Jiang, Z. Xiao, X. Fang, and Y.G. Chen, Lateral diffusion of TGF-beta type I receptor studied by single-molecule imaging. Biochem Biophys Res Commun 356 (2007) 67-71.
[6] J. Ma*, Q. Wang*, T. Fei, J.D. Han, and Y.G. Chen, MCP-1 mediates TGF-beta-induced angiogenesis by stimulating vascular smooth muscle cell migration. Blood 109 (2007) 987-94. (*Co-first author)
[7] Y.G. Chen, Q. Wang, S.L. Lin, C.D. Chang, J. Chuang, and S.Y. Ying, Activin signaling and its role in regulation of cell proliferation, apoptosis, and carcinogenesis. Exp Biol Med (Maywood) 231 (2006) 534-44.
[8] Q. Wang, Z. Bai, X. Li, L. Hou, and B. Zhang, The evidences of human orphan receptor COUP-TFII inhibiting telomerase activity through decreasing hTERT transcription. Cancer Lett 214 (2004) 81-90.
[9] J. Lv, H. Liu, Q. Wang, Z. Tang, L. Hou, and B. Zhang, Molecular cloning of a novel human gene encoding histone acetyltransferase-like protein involved in transcriptional activation of hTERT. Biochem Biophys Res Commun 311 (2003) 506-13.