Biography and Research Interest

Spine and musculoskeletal development and disease.

Publications

Non-Zebrafish Publications

Morgan RK, Anderson GR, Araç D, Aust G, Balenga N, Boucard A, Bridges JP, Engel FB, Formstone CJ, Glitsch MD, Gray RS, Hall RA, Hsiao CC, Kim HY, Knierim AB, Kusuluri DK, Leon K, Liebscher I, Piao X, Prömel S, Scholz N, Srivastava S, Thor D, Tolias KF, Ushkaryov YA, Vallon M, Van Meir EG, Vanhollebeke B, Wolfrum U, Wright KM, Monk KR, Mogha A. The expanding functional roles and signaling mechanisms of adhesion G protein-coupled receptors. Ann N Y Acad Sci. 2019 Jun 6;. doi: 10.1111/nyas.14094. [Epub ahead of print] PubMed PMID: 31168816.

Konjikusic MJ, Yeetong P, Boswell CW, Lee C, Roberson EC, Ittiwut R, Suphapeetiporn K, Ciruna B, Gurnett CA, Wallingford JB, Shotelersuk V, Gray RS. Mutations in Kinesin family member 6 reveal specific role in ependymal cell ciliogenesis and human neurological development. PLoS Genet. 2018 Nov;14(11):e1007817. doi: 10.1371/journal.pgen.1007817. eCollection 2018 Nov. PubMed PMID: 30475797; PubMed Central PMCID: PMC6307780.

Haller G, McCall K, Jenkitkasemwong S, Sadler B, Antunes L, Nikolov M, Whittle J, Upshaw Z, Shin J, Baschal E, Cruchaga C, Harms M, Raggio C, Morcuende JA, Giampietro P, Miller NH, Wise C, Gray RS, Solnica-Krezel L, Knutson M, Dobbs MB, Gurnett CA. A missense variant in SLC39A8 is associated with severe idiopathic scoliosis. Nat Commun. 2018 Oct 9;9(1):4171. doi: 10.1038/s41467-018-06705-0. PubMed PMID: 30301978; PubMed Central PMCID: PMC6177404.

Kim DH, Ewald AJ, Park J, Kshitiz, Kwak M, Gray RS, Su CY, Seo J, An SS, Levchenko A. Biomechanical interplay between anisotropic re-organization of cells and the surrounding matrix underlies transition to invasive cancer spread. Sci Rep. 2018 Sep 21;8(1):14210. doi: 10.1038/s41598-018-32010-3. PubMed PMID: 30242256; PubMed Central PMCID: PMC6155084.

Giampietro PF, Pourquie O, Raggio C, Ikegawa S, Turnpenny PD, Gray R, Dunwoodie SL, Gurnett CA, Alman B, Cheung K, Kusumi K, Hadley-Miller N, Wise CA. Summary of the first inaugural joint meeting of the International Consortium for scoliosis genetics and the International Consortium for vertebral anomalies and scoliosis, March 16-18, 2017, Dallas, Texas. Am J Med Genet A. 2018 Jan;176(1):253-256. doi: 10.1002/ajmg.a.38550. Epub 2017 Nov 21. PubMed PMID: 29159998; PubMed Central PMCID: PMC6525596.

Herbert AL, Fu MM, Drerup CM, Gray RS, Harty BL, Ackerman SD, O'Reilly-Pol T, Johnson SL, Nechiporuk AV, Barres BA, Monk KR. Dynein/dynactin is necessary for anterograde transport of Mbp mRNA in oligodendrocytes and for myelination in vivo. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9153-E9162. doi: 10.1073/pnas.1711088114. Epub 2017 Oct 12. PubMed PMID: 29073112; PubMed Central PMCID: PMC5664533.

Sanchez NE, Harty BL, O'Reilly-Pol T, Ackerman SD, Herbert AL, Holmgren M, Johnson SL, Gray RS, Monk KR. Whole Genome Sequencing-Based Mapping and Candidate Identification of Mutations from Fixed Zebrafish Tissue. G3 (Bethesda). 2017 Oct 5;7(10):3415-3425. doi: 10.1534/g3.117.300212. PubMed PMID: 28855284; PubMed Central PMCID: PMC5633390.

Karner CM, Long F, Solnica-Krezel L, Monk KR, Gray RS. Gpr126/Adgrg6 deletion in cartilage models idiopathic scoliosis and pectus excavatum in mice. Hum Mol Genet. 2015 Aug 1;24(15):4365-73. doi: 10.1093/hmg/ddv170. Epub 2015 May 7. PubMed PMID: 25954032; PubMed Central PMCID: PMC4492399.

Buchan JG, Gray RS, Gansner JM, Alvarado DM, Burgert L, Gitlin JD, Gurnett CA, Goldsmith MI. Kinesin family member 6 (kif6) is necessary for spine development in zebrafish. Dev Dyn. 2014 Dec;243(12):1646-57. doi: 10.1002/dvdy.24208. Epub 2014 Oct 20. PubMed PMID: 25283277; PubMed Central PMCID: PMC6207368.

Chen Q, Zhang N, Gray RS, Li H, Ewald AJ, Zahnow CA, Pan D. A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis. Genes Dev. 2014 Mar 1;28(5):432-7. doi: 10.1101/gad.233676.113. PubMed PMID: 24589775; PubMed Central PMCID: PMC3950341.

Gray RS, Wilm TP, Smith J, Bagnat M, Dale RM, Topczewski J, Johnson SL, Solnica-Krezel L. Loss of col8a1a function during zebrafish embryogenesis results in congenital vertebral malformations. Dev Biol. 2014 Feb 1;386(1):72-85. doi: 10.1016/j.ydbio.2013.11.028. Epub 2013 Dec 11. PubMed PMID: 24333517; PubMed Central PMCID: PMC3938106.

Nguyen-Ngoc KV, Cheung KJ, Brenot A, Shamir ER, Gray RS, Hines WC, Yaswen P, Werb Z, Ewald AJ. ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):E2595-604. doi: 10.1073/pnas.1212834109. Epub 2012 Aug 23. PubMed PMID: 22923691; PubMed Central PMCID: PMC3465416.

Gray RS, Roszko I, Solnica-Krezel L. Planar cell polarity: coordinating morphogenetic cell behaviors with embryonic polarity. Dev Cell. 2011 Jul 19;21(1):120-33. doi: 10.1016/j.devcel.2011.06.011. Review. PubMed PMID: 21763613; PubMed Central PMCID: PMC3166557.

Bhise NS, Gray RS, Sunshine JC, Htet S, Ewald AJ, Green JJ. The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures. Biomaterials. 2010 Nov;31(31):8088-96. doi: 10.1016/j.biomaterials.2010.07.023. Epub 2010 Jul 31. PubMed PMID: 20674001; PubMed Central PMCID: PMC3175420.

Gray RS, Cheung KJ, Ewald AJ. Cellular mechanisms regulating epithelial morphogenesis and cancer invasion. Curr Opin Cell Biol. 2010 Oct;22(5):640-50. doi: 10.1016/j.ceb.2010.08.019. Epub 2010 Sep 9. Review. PubMed PMID: 20832275; PubMed Central PMCID: PMC2948645.

Kim SK, Shindo A, Park TJ, Oh EC, Ghosh S, Gray RS, Lewis RA, Johnson CA, Attie-Bittach T, Katsanis N, Wallingford JB. Planar cell polarity acts through septins to control collective cell movement and ciliogenesis. Science. 2010 Sep 10;329(5997):1337-40. doi: 10.1126/science.1191184. Epub 2010 Jul 29. PubMed PMID: 20671153; PubMed Central PMCID: PMC3509789.

Kieserman EK, Lee C, Gray RS, Park TJ, Wallingford JB. High-magnification in vivo imaging of Xenopus embryos for cell and developmental biology. Cold Spring Harb Protoc. 2010 May;2010(5):pdb.prot5427. doi: 10.1101/pdb.prot5427. PubMed PMID: 20439414.

Gray RS, Abitua PB, Wlodarczyk BJ, Szabo-Rogers HL, Blanchard O, Lee I, Weiss GS, Liu KJ, Marcotte EM, Wallingford JB, Finnell RH. The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol. 2009 Oct;11(10):1225-32. doi: 10.1038/ncb1966. Epub 2009 Sep 20. PubMed PMID: 19767740; PubMed Central PMCID: PMC2755648.

Gray RS, Bayly RD, Green SA, Agarwala S, Lowe CJ, Wallingford JB. Diversification of the expression patterns and developmental functions of the dishevelled gene family during chordate evolution. Dev Dyn. 2009 Aug;238(8):2044-57. doi: 10.1002/dvdy.22028. PubMed PMID: 19618470; PubMed Central PMCID: PMC2782374.

Lee C, Kieserman E, Gray RS, Park TJ, Wallingford J. Whole-mount fluorescence immunocytochemistry on Xenopus embryos. CSH Protoc. 2008 Feb 1;2008:pdb.prot4957. doi: 10.1101/pdb.prot4957. PubMed PMID: 21356778.

Park TJ, Gray RS, Sato A, Habas R, Wallingford JB. Subcellular localization and signaling properties of dishevelled in developing vertebrate embryos. Curr Biol. 2005 Jun 7;15(11):1039-44. doi: 10.1016/j.cub.2005.04.062. PubMed PMID: 15936275.