Person

Nichols, James Tucker

Person ID
ZDB-PERS-110706-1
Email
james.nichols@ucdenver.edu
URL
Affiliation
Nichols Lab
Address
University of Colorado-Anschutz Medical Campus Department of Craniofacial Biology 12801 E. 17th Ave RC-1 South, 11th floor RM 11104 USA
Country
Phone
(303) 724-0157
Fax
ORCID ID
Biography and Research Interest
2023-present: Associate Professor, University of Colorado-Anschutz Medical Campus
2016-2023: Assistant Professor, University of Colorado-Anschutz Medical Campus
2009-2016: Postdoc, University of Oregon, Kimmel Lab
2001-2008: Graduate Student, UCLA, Weinmaster Lab
1994-1998: Undergraduate, UCSB
Publications
Non-Zebrafish Publications
Charles B. Kimmel, Sawyer Watson, Ryan B. Couture, Natasha S. McKibben, James T. Nichols, Shannon E. Richardson and David L. G. Noakes. Patterns of variation and covariation in the shapes of mandibular bones of juvenile salmonids in the genus Oncorhynchus. Evolution & Development. 2015

James T. Nichols, Gerry Weinmaster. Proteolytic activation of Notch signaling: Roles for ligand endocytosis and mechanotransduction (Book Chapter). Handbook of Cell Signaling. 2008

James T. Nichols, Alison Miyamoto, Gerry Weinmaster. Notch Signaling-constantly on the move (Review). Traffic. 2007 Aug 8; (8):959-69.

James T. Nichols, Alison Miyamoto, Samantha L. Olsen, Brendan D’Souza, Christine Yao, and Gerry Weinmaster. DSL-ligand Endocytosis Physically Dissociates Notch1 Heterodimers Before Activating Proteolysis Can Occur. Journal of Cell Biology. 2007 Feb 12; 176(4):445-58.

Ena Ladi, James T. Nichols, Alison Miyamoto, Jim Boulter, Weihong Ge, Liang-Tung Yang, Yi E. Sun, Chris Kintner and Gerry Weinmaster. The Divergent DSL Ligand Dll3 Cannot Activate Notch Signaling but Cell Autonomously Attenuates Signaling Induced by Other DSL Ligands. Journal of Cell Biology. 2005 Sep 12;170(6):983-92.

T Haritunians, T Chow, R P J De Lange, James T. Nichols, D Ghavimi, N Dorrani, D M St Clair, G Weinmaster, C Schanen. Functional analysis of a recurrent missense mutation in Notch3 in CADASIL. Journal of Neurology, Neurosurgery, and Psychiatry. 2005 Sep;76(9):1242-8

Liang-Tung Yang, James T. Nichols, Christine Yao, Jennifer O. Manilay, Ellen A. Robey, and Gerry Weinmaster. Fringe Glycosyltransferases Differentially Modulate Notch1 Proteolysis Induced by Delta1 and Jagged1. Molecular Biology of the Cell. 2005 Feb;16(2):927-42.