Biography and Research Interest

Our lab investigates the role of neurotransmitters in the development of the brain and behaviour.

Publications

Non-Zebrafish Publications

Brito-Melo GE, Nicolato R, de Oliveira AC, Menezes GB, L?lis FJ, Avelar RS, S? J, Bauer ME, Souza BR, Teixeira AL, Reis HJ. Increase in dopaminergic, but not serotoninergic, receptors in T-cells as a marker for schizophrenia severity. J Psychiatr Res. 46(6):738-42. 2012

Miranda, DM; Rosa, DVF; Magno, A; Alvim-Soares, A; Castro, CJ; Souza, BR; Romano-Silva, MA. Molecular Medicine: A path towards personalized medicine. Rev Bras Psiquiatr. 34(1):82-91. 2012.

Rosa, DV; Magno, LA; Souza, BR; Romano-Silva, MA. DARPP-32. Springer Encyclopedia of Signaling Molecules. In Press. 2012.

Souza, BR; Torres, KCL; Miranda, DM; Motta, BS; Caetano, FS; Rosa, DVF; Souza, RP; Giovani JR, A; Carneiro, DS; Guimaraes, MM; Martins-Silva, C; Reis, HJ; Gomez, MV; Jeromin, A; Romano-Silva, MA. Downregulation of the cAMP/PKA pathway in PC12 cells overexpressing NCS-1. Cellular and Molecular Neurobiology. 31:1. 2011.

Pereira, PA; Romano-Silva, MA; Bicalho, MAC; De Marco, LA; Correa, H; Campos, SB; Moraes, EN; Torres, KCL; Souza, BR; Miranda, DM. Association between Tryptophan Hydroxylase II gene and late onset depression. American Journal of Geriatric Psychiatry. 19(9):825-9. 2011

Souza, BR; Torres, KCL; Miranda, DM; Motta, BS; Scotti-Muzzi, E; Guimaraes, MM; Carneiro, DS; Rosa, DVF; Souza, RP; Reis, HJ; Jeromin, A; Romano-Silva, MA. Lack of effects of typical and atypical antipsychotics in DARPP-32 and NCS-1 levels in PC12 cells overexpressing NCS-1. Journal of Negative Results in BioMedicine. 9:4. 2010.

Campos, SB; Miranda, DM; Souza, BR; Pereira, PA; Neves, FS; Bicalho, MAC; Melilo, PH; Tramontina, J; Kapczinski, F; Romano-Silva, MA; Correa, H. Association study of tryptophan hydroxilase 2 gene polymorphisms in bipolar disorder patients with panic disorder comorbidity. Psychiatric Genetics. Online Since Nov. 16th. 2010.

Rosa, DV; Souza, RP; Souza, BR; Castro, AA; Comim, CM; Sampaio, AM; Lima, FF; Jeromin, A; Quevedo, J; Romano-Silva, MA. Inhibitory avoidance task does not change NCS-1 expression in rat brain. Brain Research Bulletin. 82:5-6. 2010.

Campos, SB; Miranda, DM; Souza, BR; Pereira, PA; Neves, FS; Bicalho, MAC; Melillo, PH; Tramontina, J; Kapczinski, F; Romano-Silva, MA; Correa, H. Association of the polymorphisms of tryptophan hydroxylase 2 gene with risk for bipolar disorder and suicidal behaviour. Journal of Psychiatric Research, 44(5):271-4. 2010.

Cordeiro, Q; Vallada, H; Souza, BR; Correa, H; Romano-Silva, MA; Guindalini, C; Hutz, MH. Population stratification in European South-American subjects and its importance to psychiatric genetics research in Brasil. Rev Bras Psiquiatr. 32(1). p. 92-94. 2010.

Cordeiro Q; Souza BR; Correa H; Guindalini C; Hutz MH; Vallada H; Romano-Silva MA. A review of psychiatric genetics research in the Brasilian population. Rev Bras Psiquiatr. v.31(2):154-62. 2009.

Souza, R; Soares, E; Rosa, D; Souza, BR; Gomes, K; Valvassori, S; Reus, G; Inacio, C; Martins, M; Gomez, M; Romano-Silva, MA. Cerebral DARPP-32 expression after methylphenidate administration in young and adult rats. International Journal of Developmental Neuroscience, v. 27, p. 1-7, 2009.

Torres, KCL; Souza, BR; Miranda, DM; Nicolato, R; Neves, FS; Barros, AGA; Dutra, WO; Gollob, KJ; Correa, H; Romano-Silva, MA. The leukocytes expressing DARPP-32 are reduced in patients with schizophrenia and bipolar disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry, v. 33, p. 214-219, 2009.

Torres, KCL; Souza, BR; Miranda, DM; Sampaio, AM; Nicolato, R; Neves, FS; Barros, AGA; Dutra, WO; Gollob, KJ; Correa, H; Romano-Silva, MA. Expression of neuronal calcium sensor-1 (NCS-1) is decreased in leukocytes of schizophrenia and bipolar disorder patients. Progress in Neuro-Psychopharmacology & Biological Psychiatry, v. 33, p. 229-234, 2009.

Souza, BR; Motta, BS; Rosa, DVF; Torres, KCL; Castro, AA; Comim, CM; Sampaio, AM; Lima, FF; Jeromin, A; Quevedo, J; Romano-Silva, MA. DARPP-32 and NCS-1 Expression is not Altered in Brains of Rats Treated with Typical or Atypical Antipsychotics. Neurochemical Research; 33(3):533-8., 2008.

Rosa, DVF; Souza, RP; Souza, BR; Guimaraes, MM; Carneiro, DS; Valvassori, SS; Gomez, MV; Quevedo, J; Romano-Silva, MA. DARPP-32 Expression in Rat Brain After an Inhibitory Avoidance Task. Neurochemical Research, 33(11):2257-62., 2008.

Souza, R; Soares, E; Rosa, D; Souza, BR; Reus, G; Barichello, T; Gomes, K; Gomez, M; Quevedo, J; Romano-Silva, M. Methylphenidate alters NCS-1 expression in rat brain. Neurochemistry International, v. 53, p. 12-16, 2008.

Rosa, DVF; Souza, RP; Souza, BR; Motta, BS; Caetano, F; Jornada, LK; Feier, G; Gomez, MV; Quevedo, J; Romano-Silva, MA. DARPP-32 expression in rat brain after electroconvulsive stimulation. Neurochemical Research, v. 32, p. 81-85, 2007.

Pimenta, FJ; Horta, MCR; Vidigal, PV; Souza, BR; De Marco, LA; Romano-Silva, MA; Gomez, RS. Decreased expression of DARPP-32 in oral premalignant and malignant lesions. Anticancer Research, v. 27, p. 2339-2343, 2007.

Reis, HJ; Rosa, DVF ; Guimaraes, MM; Souza, BR; Barros, AG; Pimenta, FJ; Souza, RP; Torres, KCL; Romano-Silva, MA. Is DARPP-32 a potential therapeutic target? Expert Opinion on Therapeutic Targets, v. 11, p. 1649-1661, 2007.

Rosa, DVF; Souza, RP; Souza, BR; Motta, BS; Caetano, FS; Jornada, LK; Feier, G; Jeromin, A; Gomez, MV; Quevedo, J; Romano-Silva, MA. NCS-1 expression in rat brain after electroconvulsive stimulation. Neurochemical Research, v. 32, p. 81-85, 2007.

Souza, RP; Rosa, DVF; Souza, BR; Romano-Silva, MA. Darpp-32. AfCS-Nature Molecule Pages, 2006. http://www.signaling-gateway.org/molecule/query?afcsid=A000752

Souza, BR; Souza, RP; Rosa, DVF; Guimaraes, MM; Correa, H; Romano-Silva, MA. Dopaminergic intracellular signal integrating proteins: relevance to schizophrenia. Dialogues in Clinical Neuroscience, v. 8, p. 95-100, 2006.