Person

Miller, Yury

Person ID
ZDB-PERS-090602-1
Email
yumiller@ucsd.edu
URL
Affiliation
Yury Miller Lab
Address
Associate Professor of Medicine University of California, San Diego 9500 Gilman Drive La Jolla, CA 92093-0682 USA
Country
United States
Phone
858-822-5771
Fax
858-534-2005
ORCID ID
Biography and Research Interest
Miller’s laboratory studies inflammatory mechanisms involved in the development of atherosclerosis. A new exciting direction in our research is studying the processes of vascular inflammation in zebrafish. The optical transparency of zebrafish larvae enables monitoring vascular lipid and macrophage accumulation in real time in a live animal. This opens endless possibilities for in vivo functional studies of certain processes of atherogenesis. We are making new transgenic zebrafish for this study. A recent advance is the development of a zebrafish with conditional expression of human oxidation-specific antibody conjugated with GFP. Upon heat shock, these zebrafish express the antibody and the GFP signal is detected to monitor in vivo accumulation of oxidized lipid in the blood vessel wall.
Publications
Non-Zebrafish Publications