Biography and Research Interest

Publications

Non-Zebrafish Publications

Inoue, M., Kamachi, Y., Matsunami, H., Imada, K., Uchikawa, M. and Kondoh, H. (2007). PAX6 and SOX2-dependent regulation of the Sox2 enhancer N-3 involved in embryonic visual system development. Genes Cells 12, 1049-1061.

Sato, N., Kamachi, Y., Kondoh, H., Shima, Y., Morohashi, K., Horikawa, R. and Ogata, T. (2007). Hypogonadotropic hypogonadism in an adult female with a heterozygous hypomorphic mutation of SOX2. Eur J Endocrinol 156, 167-171.

Yasuhara, N., Shibazaki, N., Tanaka, S., Nagai, M., Kamikawa, Y., Oe, S., Asally, M., Kamachi, Y., Kondoh, H. and Yoneda, Y. (2007). Triggering neural differentiation of ES cells by subtype switching of importin-alpha. Nat Cell Biol 9, 72-79.

Takemoto, T., Uchikawa, M., Kamachi, Y. and Kondoh, H. (2006). Convergence of Wnt and FGF signals in the genesis of posterior neural plate through activation of the Sox2 enhancer N-1. Development 133, 297-306.

Matsumata, M., Uchikawa, M., Kamachi, Y., and Kondoh, H. (2005) Multiple N-cadherin enhancers identified by systematic functional screening indicate its Group B1 SOX-dependent regulation in neural and placodal development. Dev. Biol., 286, 601-617.

Blanco, J., Girard, F., Kamachi, Y., Kondoh, H., and Gehring, WJ. (2005) Functional analysis of the chicken delta1-crystallin enhancer activity in Drosophila reveals remarkable evolutionary conservation between chicken and fly. Development. 132, 1895-1905.

Kondoh, H., Uchikawa, M., and Kamachi, Y. (2004) Interplay of Pax6 and SOX2 in lens development as a paradigm of genetic switch mechanisms for cell differentiation. Int. J. Dev. Biol. 48. 819-827.

Tanaka, S., Kamachi, Y., Tanouchi, A., Hamada, H., Jing N., and Kondoh, H. (2004) Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells. Mol. Cell. Biol., 24, 8834-8846.

Uchikawa, M., Takemoto, T., Kamachi, Y. and Kondoh, H. (2004) Efficient identification of regulatory sequences in the chicken genome by a powerful combination of embryo electroporation and genome comparison. Mech. Dev. 121, 145-1158.

Uchikawa, M., Ishida, Y., Takemoto, T., Kamachi, Y. and Kondoh, H. (2003) Functional analysis of chicken Sox2 enhancers highlights an array of diverse regulatory elements that are conserved in mammals. Dev. Cell, 4, 509-519.

Muta, M., Kamachi, Y., Yoshimoto, A., Higashi, Y. and Kondoh, H. (2002) Distinct roles of SOX2, Pax6 and Maf transcription factors in the regulation of lens-specific d1-crystallin enhancer. Genes to Cells, 7, 791-805.

Kamachi, Y., Uchikawa, M., Tanouchi, A., Sekido, R, and Kondoh, H. (2001) Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development. Genes Dev. 15, 1272-1286.

Olsson, JE., Kamachi, Y., Penning, S., Muscat, GE., Kondoh, H., and Koopman P. (2001) Sox18 expression in blood vessels and feather buds during chicken embryogenesis. Gene 271, 151-158.

Kamachi, Y., Uchikawa, M. and Kondoh, H. (2000) Pairing SOX off with partners in regulation of embryonic development. Trends Genet. 16, 182-187.

Kamachi, Y., Cheah, K.S.E. and Kondoh, H. (1999) Mechanism of regulatory target selection by the SOX High-Mobility-Group domain proteins as revealed by comparison of SOX1/2/3 and SOX9. Mol. Cell. Biol. 19, 107-120.

Uchikawa, M., Kamachi, Y. and Kondoh, H. (1999) Two distinct subgroups of Group B Sox genes for transcriptional activators and repressors: their expression during embryonic organogenesis of the chicken. Mech. Dev. 84, 103-120.

Kamachi, Y., Uchikawa, M., Collignon, J., Lovell-Badge, R. and Kondoh, H. (1998) Involvement of Sox1, 2 and 3 in the early and subsequent molecular events of lens induction. Development 125, 2521-2532.

Sekido, R., Murai, K., Kamachi, Y., and Kondoh, H. (1997) Two mechanisms in the action of repressor ƒÂEF1: binding site competition with an activator and active repression. Genes Cells. 2:771-783.

Kadokawa, Y., Kusakabe, T., Kamachi, Y., Isobe, K., Kondoh, H., and Ohyama, T. (1995) A murine Thy-1.2 reporter vector containing a SV40 origin for rapid cloning and analysis of eukaryotic promoters. Gene 153:277-278.

Kamachi, Y., Sockanathan, S., Liu, Q., Breitman, M., Lovell-Badge, R. and Kondoh, H. (1995) Involvement of SOX proteins in lens-specific activation of crystallin genes. EMBO J. 14:3510-3519.

Sekido, R., Murai, K., Funahashi, J., Kamachi, Y., Fujisawa, A., Nabeshima, Y. and Kondoh, H. (1994) The ƒÂ-crystallin enhancer-binding protein ƒÂEF1 is a repressor of E2-box-mediated gene activation. Mol. Cell. Biol. 14:5692-5700.

Funahashi, J., Sekido, R., Murai, K., Kamachi, Y. and Kondoh, H. (1993) ƒÂ-crystallin enhancer binding protein ƒÂEF1 is a zinc finger- homeodomain protein implicated in postgastrulation embryogenesis. Development 119:433-446.

Kamachi, Y. and Kondoh, H. (1993) Overlapping positive and negative regulatory elements determine lens-specific activity of the ƒÂ1-crystallin enhancer. Mol. Cell. Biol. 13:5206-5215.

Funahashi, J., Kamachi, Y., Goto, K. and Kondoh, H. (1991) Identification of nuclear factor ƒÂEF1 and its binding site essential for lens-specific activity of the ƒÂ1-crystallin enhancer. Nucleic Acids Res., 19:3543-3547.

Kamachi,Y., Ogawa, E., Asano, M., Ishida, S., Murakami, Y., Satake, M., Ito, Y. and Shigesada, K. (1990) Purification of a mouse nuclear factor that binds to both the A and B cores of the polyomvirus enhancer. J.Virology 64:4808-4819.