Biography and Research Interest

Transcriptional regulation of mesoderm and endoderm formation in zebrafish

Publications

Non-Zebrafish Publications

Wardle, F.C., Tan H. (2015) A ChIP on the shoulder? Chromatin immunoprecipitation and validation strategies for ChIP antibodies. F1000Research 2015, 4:235.

Nelson , A.C., Wardle, F.C., (2013) Conserved non-coding elements and cis-regulation: actions speak louder than words. Development 140, 1385-95.

Nelson, A.C., Pillay, N., Henderson, S., Presneau, N., Tirabosco, R., Halai, D., Berisha, F., Flicek, P., Stemple, D.L., Stern, C., Wardle, F.C., Flanagan, A.M. (2012). A gene regulatory network directed by T, brachyury gives insight into the pathogenesis of chordoma. Journal of Pathology, 228, 274-85.

Wardle, F.C., Sive, H.L. (2003). What’s your position: The Xenopus cement gland as a paradigm of regional specification. Bioessays 25, 717-726.

Wardle, F.C., Smith, J.C. (2006). Transcriptional regulation of mesendoderm formation in Xenopus. Sem Cell Dev Biol 17, 99-109.

Messenger, N.J., Kabitschke, C. Andrews, R., Grimmer, D., Núñez Miguel, R., Blundell, T.L., Smith, J.C., Wardle, F.C. (2005). Functional specificity of the T-domain protein Brachyury is conferred by its ability to interact with Smad1. Dev Cell 8, 599-610.

Taverner, N., Smith, J.C., Wardle, F.C. (2004). Identifying Transcriptional Targets. Genome Biology 5, 210

Wardle, F.C., Smith, J.C. (2004). Refinement of gene expression patterns in the early Xenopus embryo. Development 131, 4687-4696.

Bromley, E., Knapp, D., Wardle, F.C., Sun, B.I., LaVallie, E., Smith, J.C., Sive, H.L. (2004). Identification and Characterization of fullback and fullback-like two Novel Xenopus Neurotrophin Receptor Homolog Genes. Gene Expression Patterns 5, 135-140

Wardle, F.C., Wainstock, D., Sive, H. (2002). Cement gland-specific activation of the Xag1 promoter is regulated by co-operation of Ets and ATF/CREB-like binding sites. Development 129 4387-4397.

Dale, L., Wardle, F.C. (1999). A gradient of BMP activity specifies dorsal-ventral fate in the early Xenopus embryo. Sem. Cell Dev. Bio. 10, 319-326.

Wardle, F.C., Welch, J.V., Dale, L. (1999). Bone Morphogenetic Protein 1 regulates dorsal-ventral patterning in early Xenopus embryos by degrading Chordin, a BMP4 antagonist. Mech. Dev. 86 (1-2), 75-85.

Wardle, F.C., Angerer, L.M., Angerer, R.C., Dale, L. (1999). Regulation of BMP signalling by the BMP1/Tld-related metalloproteinase, SpAN. Dev. Biol. 206, 63-72.

Goodman, S.A., Albano, R., Wardle, F.C., Matthews, G., Tannahill, D., Dale, L. (1998). BMP1-related metalloproteinases promote the development of ventral mesoderm in the early Xenopus embryo. Dev. Biol. 195, 144-157.

Tannahill, D., Wardle, F.C. (1995). Control of axis formation in Xenopus by the NF-κB-IκB system. Intl. J. Dev. Biol. 39, 549-558.