Morpholino

MO2-shank3a

ID

ZDB-MRPHLNO-150925-4

Name

MO2-shank3a

Previous Names

ex10/in10 (1)

Target

shank3a (1)

Sequence

5' - AGAAAGTCTTGCGCTCTCACCTGGA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Splice-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-shank3a

No data available

Phenotype

Phenotype resulting from MO2-shank3a

Phenotype	Fish	Figures
apoptotic process increased occurrence, abnormal	nksaigff213aGt; nns14Tg + MO2-shank3a	Fig. 8 from Kozol et al., 2015
brain decreased size, abnormal	WT + MO2-shank3a	Fig. 6 from Kozol et al., 2015
brain development delayed, abnormal	WT + MO2-shank3a	Fig. 5 from Kozol et al., 2015
embryo development delayed, abnormal	WT + MO2-shank3a	Fig. 5 from Kozol et al., 2015
hindbrain apoptotic, abnormal	nksaigff213aGt; nns14Tg + MO2-shank3a	Fig. 8 from Kozol et al., 2015
hindbrain GABAergic neuron decreased amount, abnormal	WT + MO2-shank3a	Fig. 6 from Kozol et al., 2015
hindbrain glutamatergic neuron decreased amount, abnormal	WT + MO2-shank3a	Fig. 6 from Kozol et al., 2015
midbrain apoptotic, abnormal	nksaigff213aGt; nns14Tg + MO2-shank3a	Fig. 8 from Kozol et al., 2015
midbrain GABAergic neuron decreased amount, abnormal	WT + MO2-shank3a	Fig. 6 from Kozol et al., 2015
midbrain hindbrain boundary morphology, abnormal	WT + MO2-shank3a	Fig. 5 from Kozol et al., 2015
post-vent region decreased length, abnormal	WT + MO2-shank3a	Fig. 5 from Kozol et al., 2015
Rohon-Beard neuron absent, abnormal	nksaigff213aGt; nns14Tg + MO2-shank3a	Fig. 7 from Kozol et al., 2015
Rohon-Beard neuron decreased amount, abnormal	nksaigff213aGt; nns14Tg + MO2-shank3a	Fig. 7 from Kozol et al., 2015
spinal cord apoptotic, abnormal	nksaigff213aGt; nns14Tg + MO2-shank3a	Fig. 8 from Kozol et al., 2015
swimming behavior disrupted, abnormal	WT + MO2-shank3a	Fig. 3 from Kozol et al., 2015
whole organism dead, abnormal	WT + MO2-shank3a	Fig. 3 from Kozol et al., 2015

Phenotype of all Fish created by or utilizing MO2-shank3a

Phenotype	Fish	Conditions	Figures
hindbrain GABAergic neuron decreased amount, abnormal	WT + MO2-shank3a	standard conditions	Fig. 6 from Kozol et al., 2015
hindbrain glutamatergic neuron decreased amount, abnormal	WT + MO2-shank3a	standard conditions	Fig. 6 from Kozol et al., 2015
midbrain hindbrain boundary morphology, abnormal	WT + MO2-shank3a	standard conditions	Fig. 5 from Kozol et al., 2015
whole organism dead, abnormal	WT + MO2-shank3a	standard conditions	Fig. 3 from Kozol et al., 2015
embryo development delayed, abnormal	WT + MO2-shank3a	standard conditions	Fig. 5 from Kozol et al., 2015
brain development delayed, abnormal	WT + MO2-shank3a	standard conditions	Fig. 5 from Kozol et al., 2015
swimming behavior disrupted, abnormal	WT + MO2-shank3a	standard conditions	Fig. 3 from Kozol et al., 2015
post-vent region decreased length, abnormal	WT + MO2-shank3a	standard conditions	Fig. 5 from Kozol et al., 2015
midbrain GABAergic neuron decreased amount, abnormal	WT + MO2-shank3a	standard conditions	Fig. 6 from Kozol et al., 2015
brain decreased size, abnormal	WT + MO2-shank3a	standard conditions	Fig. 6 from Kozol et al., 2015
Rohon-Beard neuron decreased amount, abnormal	nksaigff213aGt; nns14Tg + MO2-shank3a	standard conditions	Fig. 7 from Kozol et al., 2015
midbrain apoptotic, abnormal	nksaigff213aGt; nns14Tg + MO2-shank3a	standard conditions	Fig. 8 from Kozol et al., 2015
spinal cord apoptotic, abnormal	nksaigff213aGt; nns14Tg + MO2-shank3a	standard conditions	Fig. 8 from Kozol et al., 2015
Rohon-Beard neuron absent, abnormal	nksaigff213aGt; nns14Tg + MO2-shank3a	standard conditions	Fig. 7 from Kozol et al., 2015
hindbrain apoptotic, abnormal	nksaigff213aGt; nns14Tg + MO2-shank3a	standard conditions	Fig. 8 from Kozol et al., 2015
apoptotic process increased occurrence, abnormal	nksaigff213aGt; nns14Tg + MO2-shank3a	standard conditions	Fig. 8 from Kozol et al., 2015
midbrain hindbrain boundary morphology, abnormal	WT + MO1-syngap1b + MO2-shank3a	standard conditions	Fig. 3 from Kozol et al., 2015
thigmotaxis disrupted, abnormal	WT + MO1-syngap1b + MO2-shank3a	standard conditions	Fig. 4 from Kozol et al., 2015
embryo development delayed, abnormal	WT + MO1-syngap1b + MO2-shank3a	standard conditions	Fig. 3 from Kozol et al., 2015
swimming behavior disrupted, abnormal	WT + MO1-syngap1b + MO2-shank3a	standard conditions	Fig. 3, Fig. 4 from Kozol et al., 2015
heart edematous, abnormal	WT + MO1-syngap1b + MO2-shank3a	standard conditions	Fig. 3 from Kozol et al., 2015
hindbrain apoptotic, abnormal	nksaigff213aGt; nns14Tg + MO1-syngap1b + MO2-shank3a	standard conditions	text only from Kozol et al., 2015
apoptotic process increased occurrence, abnormal	nksaigff213aGt; nns14Tg + MO1-syngap1b + MO2-shank3a	standard conditions	text only from Kozol et al., 2015
midbrain apoptotic, abnormal	nksaigff213aGt; nns14Tg + MO1-syngap1b + MO2-shank3a	standard conditions	text only from Kozol et al., 2015

Citations