Morpholino

MO1-lpar1

ID
ZDB-MRPHLNO-090126-5
Name
MO1-lpar1
Previous Names
  • LPA1 MO (1)
  • zlpa1 sMO1 (1)
Target
Sequence
5' - TGGAGCACTTACCCAATACAATCAC - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Splice-blocking morpholino targeting the boundary between exon 2 and intron 2.
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO1-lpar1
Expressed Gene Anatomy Figures
lpar1 Fig. 3 from Lee et al., 2008
Phenotype
Phenotype resulting from MO1-lpar1
Phenotype Fish Figures
blood circulation disrupted, abnormal AB + MO1-lpar1 text only from Lee et al., 2008
cardiovascular system morphology, abnormal y1Tg + MO1-lpar1 Fig. 5 from Lee et al., 2008
cardiovascular system non-functional, abnormal AB + MO1-lpar1 Fig. 4,  text only from Lee et al., 2008
cartilage development process quality, abnormal AB + MO1-lpar1 Fig. 1 with image from Nishioka et al., 2016
ceratohyal cartilage deformed, abnormal AB + MO1-lpar1 Fig. 1 with image from Nishioka et al., 2016
ceratohyal cartilage chondrocyte disorganized, abnormal zf678Tg + MO1-lpar1 Fig. 1 with image from Nishioka et al., 2016
ceratohyal cartilage chondrocyte increased variability of size, abnormal zf678Tg + MO1-lpar1 Fig. 1 with image from Nishioka et al., 2016
cranium malformed, abnormal zf678Tg + MO1-lpar1 Fig. 1 with image,  Fig. S1 with image from Nishioka et al., 2016
dorsal longitudinal anastomotic vessel irregular spatial pattern, abnormal y1Tg + MO1-lpar1 text only from Lee et al., 2008
gut edematous, abnormal AB + MO1-lpar1 Fig. 4 from Lee et al., 2008
head circular, abnormal AB + MO1-lpar1 Fig. 1 with image from Nishioka et al., 2016
heart contraction disrupted, abnormal AB + MO1-lpar1 text only from Lee et al., 2008
intersegmental artery decreased length, abnormal y1Tg + MO1-lpar1 (AB) Fig. 8 from Yukiura et al., 2011
intersegmental vessel irregular spatial pattern, abnormal y1Tg + MO1-lpar1 text only from Lee et al., 2008
lymphangiogenesis disrupted, abnormal y1Tg + MO1-lpar1 Fig. 5,  Fig. 6,  text only from Lee et al., 2008
Meckel's cartilage deformed, abnormal AB + MO1-lpar1 Fig. 1 with image from Nishioka et al., 2016
Meckel's cartilage chondrocyte disorganized, abnormal zf678Tg + MO1-lpar1 Fig. 1 with image from Nishioka et al., 2016
Meckel's cartilage chondrocyte increased variability of size, abnormal zf678Tg + MO1-lpar1 Fig. 1 with image from Nishioka et al., 2016
pericardium edematous, abnormal AB + MO1-lpar1 Fig. 4 from Lee et al., 2008
subintestinal vein irregular spatial pattern, abnormal y1Tg + MO1-lpar1 text only from Lee et al., 2008
supraintestinal artery irregular spatial pattern, abnormal y1Tg + MO1-lpar1 text only from Lee et al., 2008
thoracic duct aplastic, abnormal y1Tg + MO1-lpar1 Fig. 5,  Fig. 6,  text only from Lee et al., 2008
thoracic duct decreased size, abnormal y1Tg + MO1-lpar1 Fig. 6 from Lee et al., 2008
trunk edematous, abnormal y1Tg + MO1-lpar1 Fig. 4,  text only from Lee et al., 2008
Phenotype of all Fish created by or utilizing MO1-lpar1
Phenotype Fish Conditions Figures
cardiovascular system non-functional, abnormal AB + MO1-lpar1 standard conditions Fig. 4,  text only from Lee et al., 2008
blood circulation disrupted, abnormal AB + MO1-lpar1 standard conditions text only from Lee et al., 2008
cranium malformed, abnormal AB + MO1-lpar1 standard conditions Fig. 1 with image from Nishioka et al., 2016
Meckel's cartilage deformed, abnormal AB + MO1-lpar1 standard conditions Fig. 1 with image from Nishioka et al., 2016
gut edematous, abnormal AB + MO1-lpar1 standard conditions Fig. 4 from Lee et al., 2008
trunk edematous, abnormal AB + MO1-lpar1 standard conditions Fig. 4 from Lee et al., 2008
pericardium edematous, abnormal AB + MO1-lpar1 standard conditions Fig. 4 from Lee et al., 2008
cartilage development process quality, abnormal AB + MO1-lpar1 standard conditions Fig. 1 with image from Nishioka et al., 2016
ceratohyal cartilage deformed, abnormal AB + MO1-lpar1 standard conditions Fig. 1 with image from Nishioka et al., 2016
head circular, abnormal AB + MO1-lpar1 standard conditions Fig. 1 with image from Nishioka et al., 2016
heart contraction disrupted, abnormal AB + MO1-lpar1 standard conditions text only from Lee et al., 2008
thoracic duct decreased size, abnormal y1Tg + MO1-lpar1 standard conditions Fig. 6 from Lee et al., 2008
subintestinal vein irregular spatial pattern, abnormal y1Tg + MO1-lpar1 standard conditions text only from Lee et al., 2008
lymphangiogenesis disrupted, abnormal y1Tg + MO1-lpar1 standard conditions Fig. 5,  Fig. 6,  text only from Lee et al., 2008
supraintestinal artery irregular spatial pattern, abnormal y1Tg + MO1-lpar1 standard conditions text only from Lee et al., 2008
thoracic duct aplastic, abnormal y1Tg + MO1-lpar1 standard conditions Fig. 5,  Fig. 6,  text only from Lee et al., 2008
trunk edematous, abnormal y1Tg + MO1-lpar1 standard conditions text only from Lee et al., 2008
intersegmental vessel irregular spatial pattern, abnormal y1Tg + MO1-lpar1 standard conditions text only from Lee et al., 2008
dorsal longitudinal anastomotic vessel irregular spatial pattern, abnormal y1Tg + MO1-lpar1 standard conditions text only from Lee et al., 2008
cardiovascular system morphology, abnormal y1Tg + MO1-lpar1 standard conditions Fig. 5 from Lee et al., 2008
intersegmental artery decreased length, abnormal y1Tg + MO1-lpar1 (AB) standard conditions Fig. 8 from Yukiura et al., 2011
ceratohyal cartilage chondrocyte disorganized, abnormal zf678Tg + MO1-lpar1 standard conditions Fig. 1 with image from Nishioka et al., 2016
ceratohyal cartilage chondrocyte increased variability of size, abnormal zf678Tg + MO1-lpar1 standard conditions Fig. 1 with image from Nishioka et al., 2016
cranium malformed, abnormal zf678Tg + MO1-lpar1 standard conditions Fig. S1 with image from Nishioka et al., 2016
Meckel's cartilage chondrocyte disorganized, abnormal zf678Tg + MO1-lpar1 standard conditions Fig. 1 with image from Nishioka et al., 2016
Meckel's cartilage chondrocyte increased variability of size, abnormal zf678Tg + MO1-lpar1 standard conditions Fig. 1 with image from Nishioka et al., 2016
intersegmental artery attached to intersegmental vessel, abnormal y1Tg + MO1-lpar1 + MO1-lpar4 (AB) standard conditions Fig. 8 from Yukiura et al., 2011
intersegmental artery dissociated from dorsal aorta, abnormal y1Tg + MO1-lpar1 + MO1-lpar4 (AB) standard conditions Fig. 8 from Yukiura et al., 2011
intersegmental vessel decreased length, abnormal y1Tg + MO1-lpar1 + MO1-lpar4 (AB) standard conditions Fig. 8 from Yukiura et al., 2011
intersegmental artery decreased length, abnormal y1Tg + MO1-lpar1 + MO1-lpar4 (AB) standard conditions Fig. 8 from Yukiura et al., 2011
intersegmental artery decreased length, abnormal y1Tg + MO1-lpar1 + MO2-lpar4 (AB) standard conditions Fig. S5 from Yukiura et al., 2011
angiogenesis disrupted, abnormal y1Tg + MO1-lpar1 + MO2-lpar4 (AB) standard conditions Fig. S5 from Yukiura et al., 2011
intersegmental artery attached to intersegmental vessel, abnormal y1Tg + MO1-lpar1 + MO2-lpar4 (AB) standard conditions Fig. S5 from Yukiura et al., 2011
Citations
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