Morpholino

MO2-acvr1l

ID

ZDB-MRPHLNO-060920-2

Name

MO2-acvr1l

Previous Names

alk8 MO3 (1)
alk8morph2 (1)
MO2-acvr1 (1)

Target

acvr1l (1)

Sequence

5' - GATTCATGTTTGTGTTCAATTTCCG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-acvr1l

Expressed Gene	Anatomy	Figures
egr2b	presumptive rhombomere 3 presumptive rhombomere 5	Fig. 2 from Bauer et al., 2001

Phenotype

Phenotype resulting from MO2-acvr1l

Phenotype	Fish	Figures
post-vent region truncated, abnormal	WT + MO2-acvr1l	Fig. 2 from Bauer et al., 2001
whole organism wholly dorsalized, abnormal	WT + MO2-acvr1l	Fig. 5 from Umasankar et al., 2012 Fig. 2 from Bauer et al., 2001

Phenotype of all Fish created by or utilizing MO2-acvr1l

Phenotype	Fish	Conditions	Figures
post-vent region truncated, abnormal	WT + MO2-acvr1l	standard conditions	Fig. 2 from Bauer et al., 2001
whole organism wholly dorsalized, abnormal	WT + MO2-acvr1l	standard conditions	Fig. 5 from Umasankar et al., 2012 Fig. 2 from Bauer et al., 2001
blastoderm ventral region Ab13-smad labeling decreased distribution, abnormal	WT + MO2-acvr1l + MO4-acvr1l	standard conditions	Fig. 2 from Allen et al., 2020
whole organism viability, abnormal	WT + MO2-acvr1l + MO4-acvr1l	standard conditions	Fig. 1 from Allen et al., 2020
whole organism dead, abnormal	WT + MO2-acvr1l + MO4-acvr1l	standard conditions	Fig. 1 from Allen et al., 2020
whole organism dorsalized, abnormal	WT + MO2-acvr1l + MO4-acvr1l	standard conditions	Fig. 1 from Allen et al., 2020
whole organism wholly dorsalized, abnormal	WT + MO2-acvr1l + MO4-acvr1l	standard conditions	Fig. 2 from Little et al., 2009
whole organism anterior-posterior axis increased length, abnormal	WT + MO2-acvr1l + MO4-acvr1l	standard conditions	Fig. 1 from Allen et al., 2020
whole organism wholly dorsalized, abnormal	WT + MO1-fcho1 + MO2-acvr1l	standard conditions	Fig. 5 from Umasankar et al., 2012
ventral fin fold morphology, abnormal	WT + MO1-fcho1 + MO2-acvr1l	standard conditions	Fig. 5 from Umasankar et al., 2012
presumptive rhombomere 5 egr2b expression increased distribution, abnormal	bmpr1ab^sa28/sa28; bmpr1aa^p3/p3 + MO1-bmpr1ba + MO1-bmpr1bb + MO2-acvr1l + MO4-acvr1l	standard conditions	Fig. 6 from Allen et al., 2020
blastoderm ventral region Ab13-smad labeling decreased distribution, abnormal	bmpr1ab^sa28/sa28; bmpr1aa^p3/p3 + MO1-bmpr1ba + MO1-bmpr1bb + MO2-acvr1l + MO4-acvr1l	standard conditions	Fig. 5 from Allen et al., 2020
pronephric mesoderm pax2a expression absent, abnormal	bmpr1ab^sa28/sa28; bmpr1aa^p3/p3 + MO1-bmpr1ba + MO1-bmpr1bb + MO2-acvr1l + MO4-acvr1l	standard conditions	Fig. 6 from Allen et al., 2020
presumptive rhombomere 3 egr2b expression increased distribution, abnormal	bmpr1ab^sa28/sa28; bmpr1aa^p3/p3 + MO1-bmpr1ba + MO1-bmpr1bb + MO2-acvr1l + MO4-acvr1l	standard conditions	Fig. 6 from Allen et al., 2020
midbrain hindbrain boundary neural rod pax2a expression increased distribution, abnormal	bmpr1ab^sa28/sa28; bmpr1aa^p3/p3 + MO1-bmpr1ba + MO1-bmpr1bb + MO2-acvr1l + MO4-acvr1l	standard conditions	Fig. 6 from Allen et al., 2020
whole organism dorsalized, exacerbated	bmpr1ab^sa28/sa28; bmpr1aa^p3/p3 + MO1-bmpr1ba + MO1-bmpr1bb + MO2-acvr1l + MO4-acvr1l	standard conditions	Fig. 5 from Allen et al., 2020

Citations