Morpholino
MO1-gdf6a
- ID
- ZDB-MRPHLNO-050708-1
- Name
- MO1-gdf6a
- Previous Names
- Target
- Sequence
-
5' - GCAATACAAACCTTTTCCCTTGTCC - 3'
- Disclaimer
- Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
- Note
-
Splice-blocking morpholino, resulting in production of gdf6a mRNA containing its lone intron. This allows for normal maternal gdf6a function, as gdf6a is required for patterning the early embryo, but inhibits zygotic gdf6a function prior to eye development. As high levels of necrosis are observed in gdf6a morphants, gdf6a morpholinos were co-injected with a p53 translation blocking morpholino. -- French et al. 2007, ZDB-PUB-070726-17
- Genome Resources
- None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO1-gdf6a
Expressed Gene | Anatomy | Figures |
---|---|---|
en1a |
Fig. 4
from Kawakami et al., 2005 |
|
nkx2.2a |
Fig. 4
from Kawakami et al., 2005 |
|
sox10 |
Fig. 1
from Reichert et al., 2013 |
Phenotype
Phenotype resulting from MO1-gdf6a
Phenotype of all Fish created by or utilizing MO1-gdf6a
Citations