Liangyi Chen Lab

We are interested in development of state-of-the-art high spatiotemporal resolution fluorescence imaging techniques (including optics and algorithms development) for in vivo studies. We also use these new technologies to study the mechanisms of blood glucose regulation and the pathogenesis of diabetes, using zebrafish and mouse models. Specifically, with Zebrafish, we are studying the mechanisms regulating pancreatic beta cell functional maturation and the regulatory effects of alpha cells on beta cells development, function and regeneration.