ZFIN Image: Zang et al., 2024, Fig. 7.

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Figure Caption

Fig. 7.

PI3K/Akt signaling pathways identified by IPA in the zebrafish DN, early human DN and advanced human DN. PI3K/Akt signaling pathway was activated in zebrafish DN (A) and early human DN (B) but was inhibited in advanced DN (C). Upregulated and downregulated DEGs are shown in red and green, respectively, and the predicted activation and inhibition effects of signaling intermediates and pathways are shown as orange and blue lines, respectively. Asterisks in A indicate that multiple identifiers in the dataset file map to a single gene or protein in the global molecular network.

Acknowledgments

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