ZFIN Image: Huttner et al., 2023, Figure 1

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Figure Caption

Figure 1

Mapping of zebrafish (ZF) hah^vcc43 mutant. (A) Mapping of ENU mutagenesis-induced hah^vcc43 mutant to a locus on chromosome 17. The top panel shows the genome view and the bottom panel shows the chromosome view of linkage peak. (B) Candidate gene variants in linkage interval, with scfd1 variant highlighted in red box. Human variants based on full length transcripts in Ensembl. Predicted impact of amino acid variants assessed using SIFT, PMut, PolyPhen-2, and SNPs&GO. (C) Sanger sequencing confirms taT > taA codon change (red box) in ZF scfd1 gene in heterozygous (+/−) and homozygous (−/−) hah^vcc43 mutants. Created with BioRender.com.

Acknowledgments

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