ZFIN Image: Kramer et al., 2023, FIGURE 7

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Figure Caption

FIGURE 7

Transcriptomic analysis of early PR degeneration in the CLL Model. (A,B) Pairwise comparisons were performed on the 3′mRNA-seq datasets for 0 h and 5 dpl CLL model, representing a window of PR degeneration. (A) Gene ontology (GO) analysis was performed on all upregulated differentially expressed genes (DEGs) with a fold change ≥2 (FDR<0.05). Redundant terms were consolidated using REVIGO, and visualized using the CirGO visualization software. Common GO themes identified represent visual system, cell signaling, and immune system processes. (B) Select 3′mRNA-seq pseudocount graphs for genes that represent putative PR survival mechanisms.

Acknowledgments

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