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Figure 4
Loss of Jam1a reduces long-term hematopoietic reconstitution activity
(A and B) Representative result of FCM analysis in KMCs from wild-type or jam1asd43 animals under a gata2a:GFP; runx1:mCherry background.
(C) Absolute numbers of gata2a+runx1+ cells in the wild-type or jam1asd43 kidney (mean ± s.e.m; n = 16 [wild-type] or 13 [jam1asd43]).
(D) Experimental procedure for competitive repopulation assay using gata2a+runx1+ cells.
(E) Percentages of BFP+ cells within total BFP+ or dsRed+ cells in each group (mean ± s.e.m; n = 9 [wild-type] or 6 [jam1asd43]). ∗p < 0.05.
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